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BENAZEPRIL
SynDRA canonical compound SYN0002138 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACE |
|---|
| Mechanism of action | Angiotensin converting enzyme inhibitor |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- ACE inhibitor
- SLC33A1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ADRB2
- AGTR2
- PDE3A
- ESR1
- KDR
- LCK
- MAOA
- MAPK1
- MAPK14
- ABCB11
- MAPK3
- HTR7
- MC4R
- MC5R
- MLNR
- MMP1
- MMP9
- MC3R
- HTR5A
- HTR6
- NPY2R
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- GIPR
- NPY1R
- NTSR1
- NR3C1
- PTPRC
- TDP1
- TBXAS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- TP53
- SYK
- RARA
- PPARD
- NR1I2
- NR1H4
- KSYK
- HSPB1
- HIF1A
- ESRRA
- CP3A4
- CP2CJ
- CP2C9
- CP1A2
- CP19A
- CASP7
- CASP3
- ATXN2
- ATF6
- TSHR
Drug classes
- Angiotensin-converting Enzyme Inhibitors
- Angiotensin Converting Enzyme Inhibitor
- Antihypertensive Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Protease Inhibitors
ATC classes
- C09A · ACE INHIBITORS, PLAIN
- ACE INHIBITORS, COMBINATIONS
Cross-references
Synonyms
- AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE
- BENAZEPRIL HYDROCHLORIDE
- BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
- LOTENSIN
- LOTENSIN HCT
- LOTREL
- Lotensin
- Lotrel
- cibacen
- benazepril hydrochloride
- benazepril HCl
- Benazepril sandoz
- Briem
- Cibacen ws
- Cibacene
- Forteekor
- C09AA07
- CGS-14824A
- Benazapril
- Benazeprilum
- Benzazepril
- Benazepril Sandoz
- Benazeprilum [Latin]
- Forteekor [veterinary]
- Benazepril (INN)
- Benazepril Sandoz (TN)
- Benazepril [INN:BAN]
- Forteekor [veterinary] (TN)
- Fortekor (TN)
- Lotensin (TN)
- CGS-14824-A
- benazepril (ema epar veterinary)
- UDM7Q7QWP8
- CHEBI:3011
- Benazeprilum (Latin)
- benazapril
- benzazepril
- RefChem:54434
Reported adverse events
- Stevens-Johnson syndrome
- Anaphylactoid reaction
- Hypotension
- Fatigue
- Nausea
- Thrombocytopenia
- Dizziness
- Cough
- Anxiety
- Headache
- Insomnia
- Flushing
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