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TICLOPIDINE
SynDRA canonical compound SYN0002110 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | P2RY12 |
|---|
| Mechanism of action | Purinergic receptor antagonist |
|---|
| Indication | stroke | thrombosis |
|---|
| Disease area | hematology | neurology/psychiatry |
|---|
All known targets
- P2RY12
- CYP2B6
- CYP2C19
- ABCB11
- ADRA2A
- ADRA2B
- ADRA2C
- Abcb11
- CYP2A6
- CYP2D6
- PTAFR
- PTGS1
Mechanisms of action (all sources)
- Purinergic receptor antagonist
- P2RY12 ANTAGONIST
- Purinergic receptor P2Y12 antagonist
- CYP2B6 INHIBITOR
- PTAFR MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- CYP1A2
- DRD1
- ESR1
- KCNH2
- DRD4
- ADRA1A
- HTR2B
- NR1I2
- NR1I3
- NR1H4
- MLNR
- NR1H2
- NPY2R
- NPY1R
- NPSR1
- NR3C1
- MMP9
- MMP1
- NR1H3
- MC3R
- MC5R
- MC4R
- OPRD1
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- KDM4A
- IDH1
- HTR6
- HTR3A
- HTR2C
- NTSR1
- ACHE
- HTR1A
- SMN1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- KCMB2
- SYK
- PRGR
- MCL1
- M4K2
- M3K3
- KSYK
- KCMB4
- KCMB1
- ARRB1
- KCMA1
- CP3A7
- CP2D6
- CP2CJ
- CP2C9
- CP2B6
- CP1A2
- TP53
Drug classes
- Platelet Aggregation Inhibitor
- Cardiovascular Agents
- Cytochrome P-450 CYP2C19 Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Fibrinolytic Agents
- Hematologic Agents
- Metabolic Side Effects of Drugs and Substances
- Neurotransmitter Agents
- Platelet Aggregation Inhibitors
- Purinergic Antagonists
- Purinergic P2 Receptor Antagonists
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- TICLID
- TICLOPIDINE HYDROCHLORIDE
- ticlop
- ticlid
- tiklyd
- ticlopidine hydrochloride
- ticlopidine HCl
- Ticlopidina
- Ticlopidin-puren
- Ticlid
- Ticlopidinum
- PCR 5332
- Ticlid (TN)
- Ticlopidin-Puren
- Ticlopidina [INN-Spanish]
- Ticlopidine (INN)
- Ticlopidine [INN:BAN]
- Ticlopidinum [INN-Latin]
- Ticlopidin-Puren (TN)
- OM90ZUW7M1
- CHEBI:9588
- DTXCID903669
- RefChem:57660
- B01AC05
- MFCD00661081
- PCR 5332; Ticlid; Ticlop;Tiklyd
- NCGC00016872-06
- TICLOPIDINE [INN]
- UNII-OM90ZUW7M1
- SMR000641861
- CAS-55142-85-3
- EINECS 259-498-5
- BRN 1216802
- Ticlopidine (Standard)
- TICLOPIDINE [MI]
- Prestwick0_000047
- Prestwick1_000047
- Prestwick2_000047
Reported adverse events
- Agranulocytosis
- Anemia
- Aplastic anemia
- Neutropenia
- Dizziness
- Dyspepsia
- Flatulence
- Nausea
- Pain
- Pruritus
- Purpura
- Rash
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