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TIRATRICOL
SynDRA canonical compound SYN0002108 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | THRB |
|---|
| Mechanism of action | Thyroid hormone stimulant |
|---|
| Indication | Refetoff syndrome |
|---|
| Disease area | endocrinology |
|---|
All known targets
- THRB
- THRA
- AR
- PCNA
- PPARG
- RXRA
- SLC10A1
- Thrb
Mechanisms of action (all sources)
- Thyroid hormone stimulant
- THRA AGONIST
- Thyroid hormone receptor agonist
- THRB AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2A
- ESR1
- HTR1A
- ADORA3
- ADRA1A
- ADRA2A
- HTR2B
- KCNH2
- PDE4D
- NR3C1
- NR2E1
- NR2C1
- NR1I2
- NEIL2
- MUTYH
- MLNR
- MAPK1
- MC3R
- MBD4
- NR5A1
- MAOA
- LMNA
- KDR
- KAT2A
- HTR3A
- HTR2C
- NR4A1
- ABCB11
- NTHL1
- SLC6A2
- USP1
- UNG
- TRIM24
- TDG
- SMUG1
- SMN1
- SLC6A4
- SLC6A3
- SLC29A1
- OGG1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- PRGR
- NSD2
- NF2L2
- MDR1
- MDM4
- MDM2
- KCNQ1
- KCNJ1
- JUN
- HSPB1
- GSTO1
- GCR
- GABRG2
- GABRB2
- GABRA2
- GABRA1
- ESRRA
- ESR2
- CP2C9
- TP53
ATC classes
- H03A · THYROID PREPARATIONS
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
Cross-references
Synonyms
- triacana
- 3,5,3'-triiodothyroacetate
- Tiracana
- Triac
- NSC-759294
- Levothyroxine sodium impurity, triiodothyroacetic acid, or t3-acetic acid-
- T3-acetic acid
- Triiodothyroacetic acid
- TRIAC
- 3,3',5-triiodothyroacetic acid
- 3,3',5-TRIIODOTHYROACETIC ACID
- Tiratricolum
- 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
- 2-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)acetic acid
- 3',3,5-Triiodothyroacetic acid
- 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid
- NSC 759294
- DTXCID0025232
- 3,5,3'-triiodothyroacetic acid
- RefChem:190125
- D11AX08
- H03AA04
- Teatrois
- Tiratricol [INN]
- Emcitate
- Nidolin
- MFCD00055931
- 3,3',5-Triiodo Thyroacetic Acid
- [4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
- Benzeneacetic acid, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-
- Triacana
- CAS-51-24-1
- NCGC00016227-01
- Tiratricol, 3,3',5-triiodothyroacetic acid
- [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
- 3,3 inverted exclamation marka,5-Triiodothyroacetic acid
- (4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl)acetic acid
- C14H9I3O4
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