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ACEPROMAZINE
SynDRA canonical compound SYN0002058 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA1A | ADRA1B | DRD1 | DRD2 | HTR1A | HTR2A |
|---|
| Mechanism of action | dopamine receptor antagonist |
|---|
| Indication | sedative |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD1
- DRD2
- ADRA1A
- ADRA1B
- HTR1A
- HTR2A
- PRNP
Mechanisms of action (all sources)
- dopamine receptor antagonist
- DRD1 ANTAGONIST
- DRD2 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- OPRM1
- CHRM1
- CHRM2
- SLC6A4
- SLC6A2
- KCNH2
- DRD3
- ACHE
- PDE4A
- LMNA
- MAOA
- PABPC1
- PDE3A
- SAMHD1
- PGR
- PTGS1
- SLC6A3
- SMAD3
- TBXA2R
- TDP1
- KDR
- HTR2B
- IDH1
- CYP2D6
- AR
- ATXN2
- CBX1
- CYP1A2
- CYP2C19
- CYP2C9
- CYP3A4
- ADORA3
- ESR1
- F2
- GLP1R
- GMNN
- HDAC6
- HRH3
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- CP1A2
- CP2D6
- CP3A7
- KSYK
- MAPT
- MDR1
- SMAD2
- SYK
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- PROMACE
- acetylpromazine
- acepromazin
- acetacin
- acetazin
- acetazine
- acetopromazine
- azepromazine
- acetopromazine maleate
- acetopromazine maleate salt
- acepromazine maleate
- Acepromazina
- Acetylpromazine
- Acezine 2
- Atravet
- Concentrat vo34
- ace
- acp
- Acetopromazine
- Acepromazinum
- CHEBI:44932
- RefChem:53844
- DTXCID502552
- N05AA04
- Azepromazine
- Notensil
- Plivafen
- Atsetozin
- Acepromazin
- Acetacin
- Acetazin
- Promazine, acetyl-
- 2-Acetylpromazine
- SV-1522
- 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanone
- WY-1172
- 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
- AY-57,062
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