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FLUVOXAMINE
SynDRA canonical compound SYN0001995 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP2C19 | SLC6A4 |
|---|
| Mechanism of action | selective serotonin reuptake inhibitor (SSRI) |
|---|
| Indication | obsessive compulsive disorder (OCD) |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A4
- CYP1A2
- CYP2C19
- SIGMAR1
- SLC6A2
- SLC6A3
- Sigmar1
- Slc6a4
- Tmem97
Mechanisms of action (all sources)
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- selective serotonin reuptake inhibitor (SSRI)
- SLC6A4 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- CYP2C9
- CYP2D6
- KCNH2
- ABCB1
- LMNA
- NPSR1
- NFKB1
- MLNR
- MC4R
- MC3R
- MAOA
- KMT2A
- NR1I2
- IDH1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- NPY1R
- NR3C1
- HRH1
- SCN5A
- TRPV1
- TDP1
- TBXA2R
- SMN1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC29A1
- SAMHD1
- OPRD1
- PTGS2
- POLI
- PMP22
- PGR
- PDE4D
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- ESR2
- TNNT2
- TNNI3
- TNNC1
- RARA
- JUN
- GLI3
- ESRRA
- CP3A7
- ANDR
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- CP19A
- APAF
- TSHR
Drug classes
- Serotonin Uptake Inhibitors
- Serotonin Reuptake Inhibitor
- Anti-Anxiety Agents
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Central Nervous System Agents
- Central Nervous System Depressants
- Cytochrome P-450 CYP1A2 Inhibitors
- Cytochrome P-450 CYP2C19 Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Membrane Transport Modulators
ATC classes
Cross-references
Synonyms
- FLUVOXAMINE MALEATE
- LUVOX
- LUVOX CR
- fluvoxamine maleate
- depromel
- Fluvoxamina
- N06AB08
- Dumyrox
- Fluvoxaminum
- Fluvoxamina [INN-Spanish]
- Fluvoxamine (INN)
- Fluvoxamine [INN:BAN]
- Fluvoxamine-CR
- Fluvoxaminum [INN-Latin]
- Luvox (TN)
- 2-[({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine
- O4L1XPO44W
- CHEBI:5138
- DTXCID0024002
- Dumirox
- Nu Fluvoxamine
- Novo Fluvoxamine
- PMS Fluvoxamine
- ratio-Fluvoxamine
- Fluvoxamin ratiopharm
- Geminis, Fluvoxamina
- Fluvoxamin neuraxpharm
- RefChem:56865
- C15H21F3N2O2
- (Z)-Fluvoxamine
- FLUVOXAMINE [INN]
- CAS-54739-18-3
- UNII-O4L1XPO44W
- FluvoxaMine?
- NCGC00018193-06
- FVX
- PS22 - Fluvoxamine
- Fluvoxamine (Standard)
Reported adverse events
- Suicide
- Stevens-Johnson syndrome
- Agitation
- Amblyopia
- Anorgasmia
- Anxiety
- Asthenia
- Chills
- Constipation
- Depression
- Dizziness
- Dyspepsia
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