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PIRACETAM
SynDRA canonical compound SYN0001970 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | GRIA1 | GRIA2 | GRIA3 | GRIA4 |
|---|
| Mechanism of action | acetylcholine receptor agonist |
|---|
| Indication | senile dementia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- GRIA1 POSITIVE ALLOSTERIC MODULATOR
- GRIA2 POSITIVE ALLOSTERIC MODULATOR
- GRIA3 POSITIVE ALLOSTERIC MODULATOR
- GRIA4 POSITIVE ALLOSTERIC MODULATOR
- acetylcholine receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- KCNH2
- MPHOSPH8
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KAT2A
- NPY2R
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GNAS
- NPY1R
- NR1I2
- ADORA1
- SAMHD1
- TSHR
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Central Nervous System Agents
- Neuroprotective Agents
- Nootropic Agents
- Protective Agents
ATC classes
- N06B · PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Cross-references
Synonyms
- 2-Pyrrolidinoneacetamide
- neuracetam
- pirazetam
- nootropil
- Myocalm
- CL-871
- NSC-758191
- Gabacet
- Nootrop
- Nootrop 1200
- Nootrop 400
- Nootrop 800
- Nootropil
- Nootropyl
- KT-801
- 2-(2-oxopyrrolidin-1-yl)acetamide
- 2-Oxo-1-pyrrolidineacetamide
- Normabrain
- Pyracetam
- Pyramem
- Pirazetam
- Piracetamum
- Cl-871
- 1-Acetamido-2-pyrrolidinone
- 2-Ketopyrrolidine-1-ylacetamide
- NSC 758191
- ZH516LNZ10
- DTXCID3024491
- Piracetam-RPh
- Memo Puren
- 2-Pyrrolidone-N-Acetamide
- UCB6215
- RefChem:6146
- N06BX03
- 1-Pyrrolidineacetamide, 2-oxo-
- Euvifor
- Genogris
- Pirroxil
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