← SynDRA
FLUTAMIDE
SynDRA canonical compound SYN0001951 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | AR |
|---|
| Mechanism of action | Androgen receptor antagonist |
|---|
| Indication | prostate cancer |
|---|
| Disease area | oncology |
|---|
All known targets
- AR
- AHR
- Abcb11
- Ar
- CYP1A2
- CYP2C19
- HTR4
- HTR6
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AADAC
- TBXA2R
- ESR1
- ESR2
- KCNH2
- NR1I2
- CES2
- DRD2
- ADRA1A
- CHRM1
- NR3C1
- MC4R
- OPRD1
- OPRK1
- NPY1R
- NFE2L2
- MPHOSPH8
- MMP9
- MMP1
- MLNR
- MC5R
- NPY2R
- MAPK3
- MC3R
- MBNL1
- PDE3A
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDR
- HTT
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRM1
- PDE5A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- KCMA1
- SMAD3
- SMAD2
- RXRA
- RARA
- PRGR
- NF2L2
- MDR1
- KSYK
- INS
- CP19A
- GLI3
- ESRRA
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- SYK
Drug classes
- Androgen Receptor Antagonists
- Androgen Receptor Inhibitor
- Androgen Antagonists
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Hormone Antagonists
ATC classes
- L02B · HORMONE ANTAGONISTS AND RELATED AGENTS
Cross-references
Synonyms
- EULEXIN
- Eulexin
- flutopharm
- niftholide
- niftolide
- Flutamida
- NSC-215876
- SCH-13521
- Chimax
- Drogenil
- Apimid
- ApoFlutamide
- Cebatrol
- Cytamid
- Eulexine
- Fluken
- Flulem
- Flumid
- FlutaGRY
- Flutacell
- Flutamidum
- Flutamin
- Flutandrona
- Flutaplex
- Flutexin
- Fugerel
- METHOXYCHLOR
- NFBA
- Niftholide
- Niftolid
- Niftolide
- NovoFlutamide
- Odyne
- Oncosal
- Prostacur
- Prostandril
- Prostica
Reported adverse events
- Nausea
- Cystitis
- Proctitis
- Vomiting
Look up FLUTAMIDE in the interactive SynDRA portal →