← SynDRA
FENBENDAZOLE
SynDRA canonical compound SYN0001947 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | TUBB |
|---|
| Mechanism of action | Tubulin inhibitor |
|---|
| Indication | gastrointestinal parasites | gastrointestinal roundworms |
|---|
| Disease area | infectious disease |
|---|
All known targets
- TUBB
- CYP2C19
- CYP2D6
- CYP2J2
- CYP3A4
- MAPK14
- penPC
Mechanisms of action (all sources)
- microtubule inhibitor
- tubulin polymerization inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR1
- MAPK1
- NPY1R
- NFE2L2
- MMP9
- MMP1
- METAP2
- METAP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAOA
- HDAC6
- LMNA
- LCK
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH2
- HRH1
- NPY2R
- ACHE
- NR3C1
- SIGMAR1
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMAD3
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- A4
- JUN
- TP53
- SYK
- STK33
- STAT1
- SMAD2
- PRGR
- PPARD
- NSD2
- NR1H4
- NF2L2
- MDR1
- KSYK
- JAK2
- AHR
- IFNG
- IDHC
- HTR1E
- GLI3
- GEMI
- GCR
- ESRRA
- CP2CJ
- CP1A2
- CASP7
- CASP3
- ANDR
- VDR
Drug classes
- Anthelmintics
- Anti-Infective Agents
- Antinematodal Agents
- Antiparasitic Agents
ATC classes
- P02C · ANTINEMATODAL AGENTS
Cross-references
Synonyms
- Panacur
- Safe-Guard
- fenbendazol
- febendazole
- phenbendasol
- Fenbendazol
- Fenbendazole for veterinary use
- Panacur aquasol
- HOE-881V
- HOE-881Y
- NSC-757824
- Phenbendasol
- Fenbendazolum
- Methyl 5-(phenylthio)-2-benzimidazolecarbamate
- HOE-881v
- Safe-quard
- 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole
- methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate
- methyl (6-(phenylthio)-1H-benzo[d]imidazol-2-yl)carbamate
- Fenbendazole (Panacur)
- Fenbendazole (USP/INN)
- MFCD00144301
- NSC 757824
- Methyl (5-(phenylthio)-1H-benzimidazol-2-yl)carbamate
- CHEMBL37161
- 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester
- MLS000069723
- HOE 881Y
- 2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester
- CHEBI:77092
- HOE 881
- 621BVT9M36
- methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate
- NCGC00016855-01
- SMR000058217
- CAS-43210-67-9
- methyl (5-(phenylthio)-1H-benzo[d]imidazol-2-yl)carbamate
- Fenbendazole D3 (methyl D3)
Look up FENBENDAZOLE in the interactive SynDRA portal →