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CILOSTAMIDE
SynDRA canonical compound SYN0001918 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PDE3B |
|---|
| Mechanism of action | Phosphodiesterase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- PDE3A INHIBITOR
- PDE3B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTAFR
- ESR1
- DRD2
- PDE5A
- ABL1
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR2C
- HTR2B
- MC5R
- HTR2A
- HSD17B10
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- GSK3B
- FYN
- FLT1
- FGFR2
- MC4R
- MMP9
- MMP1
- PTPRC
- TSHR
- TRIM24
- TDP1
- TBXAS1
- TACR2
- TACR1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP3A4
- CP3A7
- GLI3
- NR1I2
- NTM1A
Drug classes
- Phosphodiesterase Inhibitors
- Platelet Aggregation Inhibitors
Cross-references
Synonyms
- Cilostamida
- OPC-3689
- ciloalamide
- OPC 3689
- Cilostamide [INN]
- N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
- Cilostamidum [INN-Latin]
- Cilostamida [INN-Spanish]
- UNII-45S5605Q18
- OPC 3869
- CHEMBL34431
- NCGC00015269-03
- N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide
- 45S5605Q18
- Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-
- N-Cyclohexyl-N-methyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide
- DSSTox_RID_80698
- DSSTox_CID_25140
- DSSTox_GSID_45140
- Cilostamidum
- N-Cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolyl)oxy)-N-methylbutyramide
- N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
- CAS-68550-75-4
- SR-01000075781
- MFCD00673958
- Tocris-0915
- CILOSTAMIDE [JAN]
- Lopac-C-7971
- Cilostamide (OPC 3689)
- Lopac0_000288
- SCHEMBL49742
- GTPL5167
- DTXSID3045140
- BDBM15297
- CHEBI:92503
- HMS2090J06
- HMS3260J18
- HMS3267A21
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