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METHYLPHENIDATE
SynDRA canonical compound SYN0001907 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A3 |
|---|
| Mechanism of action | Dopamine-norepinephrine reuptake inhibitor |
|---|
All known targets
- SLC6A3
- SLC6A2
- ADRA2A
- ADRA2B
- ADRA2C
- SLC6A4
- Slc6a3
Mechanisms of action (all sources)
- Dopamine-norepinephrine reuptake inhibitor
- SLC6A3 INHIBITOR
- Dopamine transporter inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
- SLC6A3 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- CYP2D6
- HDAC6
- KAT2A
- LMNA
- NFE2L2
- PPARD
- SLC47A1
- SLC47A2
- TDP1
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Central Nervous System Agents
- Central Nervous System Stimulants
- Dopamine Agents
- Dopamine Uptake Inhibitors
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Central Nervous System Stimulant
ATC classes
- N06B · PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Cross-references
Synonyms
- ADHANSIA XR
- APTENSIO XR
- Aptensio
- CONCERTA
- COTEMPLA XR-ODT
- Concerta
- DAYTRANA
- Daytrana
- JORNAY PM
- METADATE CD
- METADATE ER
- METHYLIN
- calocain
- methylphenidan
- phenidylate
- methylphenidate hydrochloride
- concerta
- methylphenidate HCl
- Metilfenidato
- Methylphenidate extended release
- Prc-063
- Threo-dl-methylphenidate
- Cotempla xr-odt
- Calocain
- Centedein
- Centedrin
- Centredin
- Meridil
- Methylfenidan
- Methylofenidan
- Methylphen
- Methylphenidan
- Methylphenidatum
- Phenidylate
- Plimasine
- Riphenidate
- Ritaline
- Tsentedrin
Reported adverse events
- Sudden death
- Raynaud's phenomenon
- Dependence
- Anxiety
- Increased blood pressure
- Priapism
- Glaucoma
- Hypertensive crisis
- Nervousness
- Insomnia
- Hypersensitivity
- Abdominal pain
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