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LIPOIC ACID, ALPHA
SynDRA canonical compound SYN0001838 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ACHE | ALDH2 | PTGS2 |
|---|
| Mechanism of action | reducing agent |
|---|
| Indication | diabetic nephropathy |
|---|
| Disease area | nephrology |
|---|
All known targets
- ACHE
- PTGS2
- ALDH2
- SAE1
- TARDBP
- UBA2
- glmU
Mechanisms of action (all sources)
- PTGS2 INHIBITOR
- ACHE INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- PDE3A
- OPRK1
- OPRD1
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- NOS1
- NFE2L2
- MPHOSPH8
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- L3MBTL1
- KDR
- KCNH2
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRM1
- PDE4A
- HSD17B10
- PDE5A
- TSHR
- THRB
- TDP1
- TBXAS1
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- ANDR
- CAC1B
- COPS5
- CP2CJ
- DPOLB
- DUS3L
- GPX1
- IF4G1
- JUN
- LMBL1
- MBD2
- MCL1
- NF2L2
- UHRF1
Drug classes
- Antioxidants
- Micronutrients
- Protective Agents
- Vitamin B Complex
- Vitamins
- reducing agent
ATC classes
- A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Cross-references
Synonyms
- thioctic acid
- lipothion
- thioctacid
- thioctsan
- tioctacid
- (RS)-Lipoic acid
- alpha lipoic acid
- lipoic acid
- Thioctic acid
- Thioctic acid dl-form
- .alpha.-lipoic acid
- 6,8-thioctic acid
- A-lipoicum acidum
- Acidum thiocticum
- Alpha lipoic acid
- Biletan
- Dl-6,8-thioctic acid
- Lipoic acid, dl-
- Thiocacid
- Thioctan
- Thioctate
- Tioctic acid
- NSC-628502
- NSC-90788
- Thioctacid
- Losartan/thioctic acid
- Lipoic acid
- (R)-lipoic acid
- R-(+)-alpha-Lipoic acid
- (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid
- Heparlipon
- Thioctic acid d-form
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
- R-alpha-Lipoic acid
- (R)-1,2-Dithiolane-3-pentanoic acid
- Tioctic Acid
- D-Thioctic acid
- R-(+)-Thioctic acid
- (R)-alpha-Lipoic acid
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