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IODOMELATONIN
SynDRA canonical compound SYN0001804 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | NQO2 |
|---|
| Mechanism of action | Melatonin receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- Melatonin receptor agonist
- MTNR1A FULL AGONIST
- MTNR1B FULL AGONIST
- MTNR1A AGONIST
- MTNR1B INHIBITOR
- NQO2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADGRF1
- ADRA2A
- TSHR
- TDG
- SMUG1
- S1PR1
- OGG1
- NTHL1
- NEIL1
- MUTYH
- MPG
- MBD4
- HDAC6
- GPR35
- GPR119
- GLP1R
- FPR2
- FFAR4
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CX3CR1
- C5AR1
- APLNR
- APEX1
- AGTR1
- ADRB2
- UNG
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2CJ
- CP2D6
- CP3A4
- MTR1B
Cross-references
Synonyms
- 2-iodo-melatonin
- 2-Iodomelatonin
- n-[2-(2-iodo-5-methoxy-1h-indol-3-yl)ethyl]acetamide
- CHEMBL289233
- N-(2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl)acetamide
- acetamide,n-[2-(2-iodo-5-methoxy-1h-indol-3-yl)ethyl]-
- Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-, (3beta)-
- Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-
- SR-01000075935
- 2-I-MLT
- Melatonin,2-Iodo
- ML2
- Tocris-0737
- Lopac-I-1899
- AC1L3GZ8
- AC1Q5P6Z
- Lopac0_000610
- SCHEMBL163451
- GTPL1343
- BDBM29611
- CTK8F4316
- DTXSID30239462
- 2-IODOMELATONIN
- 2Q5TZ5754A
- N-(2-(2-iodo-5-methoxy-IH-indol-3-yl)ethyl)acetamide
- acetamide, N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]-
- RefChem:824686
- DTXCID50161953
- N-Acetyl-2-iodo-5-methoxytryptamine
- MFCD00055216
- FJDDSMSDZHURBJ-UHFFFAOYSA-N
- UNII-2Q5TZ5754A
- orb1710608
- CHEBI:109558
- HMS3266P03
- HMS3411F09
- HMS3675F09
- HMS3753E03
- EX-A7637
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