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CLAVULANIC ACID
SynDRA canonical compound SYN0001795 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | beta lactamase inhibitor |
|---|
| Indication | otitis |
|---|
| Disease area | otolaryngology |
|---|
All known targets
- BlaGIL-1
- Stap-coc blaZ
- blaZ
- blaUOE-1
- blaTEM-125
- blaT-4
- blaT-3
- blaSHV-72
- blaSHV-55
- blaSCO-1
- blaPER-2
- blaGES-13
Mechanisms of action (all sources)
- beta lactamase inhibitor
- Stap-coc blaZ INHIBITOR
- bla INHIBITOR
- blaT-3 INHIBITOR
- blaT-4 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCC2
- ELANE
- GHSR
- HRH1
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NR1I2
- NR3C1
- OPRD1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- ESR1
- EDNRA
- ABCC3
- DRD3
- ABCC4
- ADORA1
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- beta Lactamase Inhibitors
- beta Lactamase Inhibitor
- Anti-Bacterial Agents
- Anti-Infective Agents
- beta-Lactamase Inhibitors
- Enzyme Inhibitors
Cross-references
Synonyms
- AMOXICILLIN AND CLAVULANATE POTASSIUM
- AUGMENTIN '125'
- AUGMENTIN '200'
- AUGMENTIN '250'
- AUGMENTIN '400'
- AUGMENTIN '500'
- AUGMENTIN '875'
- AUGMENTIN ES-600
- AUGMENTIN XR
- Augmentin
- TIMENTIN
- TIMENTIN IN PLASTIC CONTAINER
- clavulanate
- clavulanate potassium
- clavulante potasium
- clavulanate potassium salt
- Acide clavulanique
- Acido clavulanico
- Clavulanate
- Serdaxin
- BRL-14151
- RX-10100
- Clavulansaeure
- Clavulox
- Acidum clavulanicum
- Clavulansaeure [INN]
- Clavulinic Acid
- Sodium Clavulanate
- Antibiotic MM 14151
- MM-14151
- Acide clavulanique [INN-French]
- Acido clavulanico [INN-Spanish]
- Acidum clavulanicum [INN-Latin]
- Clavulanic acid (INN)
- Clavulanic acid [BAN:INN]
- Clavulox (TN)
- 3008-B
Reported adverse events
- Hypersensitivity
- Agitation
- Stevens-Johnson syndrome
- Death
- Anaphylactic reaction
- Abdominal discomfort
- Thrombocytosis
- Rash
- Enterocolitis
- Pruritus
- Crystalluria
- Nausea
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