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RESERPINE
SynDRA canonical compound SYN0001777 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | SLC18A2 |
|---|
| Mechanism of action | Vesicular monoamine transporter inhibitor |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- SLC18A2
- SLC18A1
- ABCB1
- ABCG2
- DRD1
- DRD2
- DRD3
- HTR1A
- OPRM1
- SCN1A
- SCN2A
- SCN3A
Mechanisms of action (all sources)
- Vesicular monoamine transporter inhibitor
- SLC18A2 INHIBITOR
- Synaptic vesicular amine transporter inhibitor
- SLC18A2 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- ACHE
- NR1I2
- BCHE
- ESR1
- KCNH2
- ADRB2
- MMP9
- MBNL1
- MC3R
- MC4R
- MC5R
- MLNR
- MMP1
- MPHOSPH8
- MAPK3
- NFE2L2
- NFKB1
- NPSR1
- NPY1R
- NPY2R
- NR1H4
- NR3C1
- MAPT
- MAPK1
- MAPK14
- KAT2A
- HSD17B10
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- HTR6
- IDH1
- KDM4A
- OPRK1
- KDM4E
- KDR
- KMT2A
- L3MBTL1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- PSMB3
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB4
- AHR
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- RAN
- SSPN
- TP53
- PSMA4
- PSMA3
- PSMA2
- PSMA1
- ANDR
- CASP3
- CP19A
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- ESRRA
- GCR
- GEMI
- GLI3
- GLSK
- KPNB1
- MDR1
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antihypertensive Agents
- Antipsychotic Agents
- Cardiovascular Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
- C02A · ANTIADRENERGIC AGENTS, CENTRALLY ACTING
- ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Cross-references
Synonyms
- CAM-AP-ES
- CHLOROTHIAZIDE AND RESERPINE
- CHLOROTHIAZIDE W/ RESERPINE
- CHLOROTHIAZIDE-RESERPINE
- DEMI-REGROTON
- DIUPRES-250
- DIUPRES-500
- DIUTENSEN-R
- DRALSERP
- H.R.-50
- HISERPIA
- HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE AND RESERPINE
- deserpine
- elserpine
- rauwasedin
- rivasin
- serpine
- Reserpina
- Apoplon
- Reserpinum
- ENT-50146
- NSC-237659
- NSC-59272
- Hiserpia
- Rau-sed
- Reserpine component of cam-ap-es
- Reserpine component of demi-regroton
- Reserpine component of diutensen-r
- Reserpine component of dralserp
- Reserpine component of h.r.-50
- Reserpine component of hydralazine hydrochloride-hydrochlorothiazide-
- Reserpine component of hydrap-es
- Reserpine component of hydro-reserp
- Reserpine component of hydromox r
- Reserpine component of hydropres
- Reserpine component of hydroserpine plus (r-h-h)
- Reserpine component of metatensin
- Reserpine component of naquival
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