← SynDRA

CYCLOSERINE

SynDRA canonical compound SYN0001772 — structure-anchored drug synonym record

All known targets

• GRIN1
• CYP3A4
• Grin2b
• alr
• MycB ddl
• MycB alr
• Grin3b
• Grin3a
• Grin2d
• Grin2c
• Grin2a
• Grin1

Mechanisms of action (all sources)

• bacterial cell wall synthesis inhibitor
• MycB ddl INHIBITOR
• MycB alr INHIBITOR
• GRIN1 INHIBITOR
• ddl INHIBITOR
• alr INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• ADORA3
• KCNH2
• KDR
• LMNA
• MAOA
• MAPK1
• MPHOSPH8
• OPRM1
• PDE3A
• PDE4A
• PGR
• PTGS1
• RGS4
• SAMHD1
• SLC6A2
• SLC6A3
• SLC6A4
• SMN1
• TBXA2R
• TDP1
• HTR2B
• HTR1A
• HSD17B10
• CYP2C19
• ADRA1A
• ADRA2A
• AR
• BLM
• CBX1
• CHRM1
• CHRM2
• CYP1A2
• CYP2C9
• HRH3
• CYP2D6
• DRD1
• DRD3
• EHMT2
• ESR1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• GPR151

Drug classes

• Anti-Bacterial Agents
• Anti-Infective Agents
• Anti-Infective Agents, Urinary
• Antibiotics, Antitubercular
• Antimetabolites
• Antitubercular Agents
• Noxae

ATC classes

• J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS

Cross-references

• PubChem CID: 6234
• ChEMBL: CHEMBL771
• DrugBank: DB00260
• ChEBI: CHEBI:23503
• KEGG: D00877
• RxNorm: 3007
• PDB: 4AX
• Wikipedia: Cycloserine
• TTD: D02WFK
• LINCS BRD: BRD-K87226815

Synonyms

• SEROMYCIN
• Seromycin
• seromycin
• oxamycin
• farmiserina
• miroseryn
• cyclorin
• Cicloserina
• Cycloserinum
• D-cycloserine
• Orientomycin
• NSC-154851
• NSC-76029
• orientomycin
• Oxamycin
• Cyclorin
• Cyclo-D-serine
• Wasserina
• Farmiserina
• Tisomycin
• Miroseryn
• Closina
• D-4-amino-3-isoxazolidinone
• alpha-Cycloserine
• (+)-4-Amino-3-isoxazolidinone
• Miroserina
• D-4-amino-3-isoxazolidone
• Oxamicina
• PA-94
• (+)-Cycloserine
• Oxamicina [Italian]
• Cycloserin
• Micoserina
• Cicloserina [Italian]
• Tebemicina
• Novoserin
• D-Oxamycin
• Closerin

Reported adverse events

• Aggression
• Coma
• Dysarthria
• Headache
• Hyperreflexia
• Paresis
• Tremor
• Vertigo