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FISETIN
SynDRA canonical compound SYN0001754 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CDK6 |
|---|
| Mechanism of action | Aurora kinase inhibitor |
|---|
All known targets
- CDK6
- FASN
- AKR1B1
- AURKB
- Malaria FabZ
- Malaria fabG
- Malaria fabI
- SIRT1
Mechanisms of action (all sources)
- aurora kinase inhibitor
- CDK6 INHIBITOR
- Malaria fabI INHIBITOR
- Malaria fabG INHIBITOR
- FASN INHIBITOR
- Malaria FabZ INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- XDH
- FTO
- RPS6KA2
- RPS6KA1
- CDK2
- SLCO2B1
- HDAC6
- CSNK2A1
- RPS6KA3
- SYK
- ACHE
- ALOX15
- ALOX12
- PKM
- PIM1
- SLC16A1
- SLCO1B1
- RAPGEF3
- RECQL
- RACGAP1
- POLK
- POLI
- POLH
- SLCO1B3
- TDP1
- SMAD3
- NR3C1
- WRN
- ULK1
- UGT2B15
- UGT1A9
- UGT1A8
- UGT1A6
- UGT1A4
- UGT1A3
- UGT1A10
- UGT1A1
- TYMS
- TP53
- TOP2B
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABL1
- NTMT1
- LOX15
- M3K5
- MAPK10
- MAPK14
- MK01
- NOD2
- NTM1A
- PA1B3
- KSYK
- PAFA2
- PIM2
- PSIP1
- RBBP8
- RGAP1
- RIN1
- RIPK2
- LOX12
- IL1B
- CASP6
- CLK1
- CCNB1
- CCNB2
- CCNB3
- CD5R1
- CDK1
- CDK5
- CDK5R1
- CP1A2
- GSK3B
- CP2C9
- CP3A4
- CSNK2A2
- CSNK2A3
- CSNK2B
- FUMH
- GSK3A
- STK16
Cross-references
Synonyms
- 5-desoxyquercetin
- C.i. 75620
- C.i. natural brown 1
- Fisidenolon 1521
- NSC-407010
- NSC-656275
- 3,7,3',4'-TETRAHYDROXYFLAVONE
- 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
- 5-Desoxyquercetin
- Fustel
- Cotinin
- Viset
- 3,3',4',7-Tetrahydroxyflavone
- Fisetholz
- Superfustel
- Fustet
- Fietin
- Junger fustik
- Ventin sumach
- Zante fustic
- Young fustic
- Superfustel K
- Ungarisches gelbholz
- CI Natural Brown 1
- Young fustic crystals
- Bois bleu de Honqrie
- BOIS bleude honqrie
- CI 75620
- NSC 407010
- NSC 656275
- 5-Deoxyquercetin
- 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
- Natural Brown 1
- 3,7,3',4'-Tetrahydroxyflavone
- C.I. Natural Brown 1
- C.I. 75620
- 7,3',4'-Trihydroxyflavonol
- 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
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