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WAY-100,635
SynDRA canonical compound SYN0001726 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | HTR1A |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- HTR1A ANTAGONIST
- DRD4 FULL AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- HTR7
- ADRA1B
- HTR1B
- DRD2
- HTR2B
- ADRA1D
- SIGMAR1
- RGS4
- PTH1R
- PMP22
- NFE2L2
- HTR2A
- KCNH2
- SLC6A4
- HTR6
- HTR5A
- SMN1
- HTR3A
- HTR2C
- TDP1
- LMNA
- HTR1D
- HTR1E
- ATAD5
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- ADRB3
- BLM
- HDAC6
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- EHMT2
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- ALR
- CP3A4
- DRD3
- PI4K2A
Cross-references
Synonyms
- Way 100635
- N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide
- UNII-71IH826FEG
- CHEMBL31354
- 71IH826FEG
- WAY100635
- Rec 0/0277
- [3H]WAY100635
- Lopac-W-108
- AC1L1KWK
- GTPL80
- AC1Q5IB0
- SCHEMBL84178
- Lopac0_001229
- WAY-100635 maleate salt/
- GTPL3251
- BDBM86708
- DTXSID20167467
- CHEBI:125619
- EX-A1053
- ZINC52541473
- 2799AH
- PDSP2_001699
- PDSP1_001716
- ABP000343
- AKOS027313833
- SB19513
- NSC_104911
- CS-0418
- CCG-205303
- WAY-100635
- WAY 100,635
- WAY100,635
- RefChem:934174
- DTXCID3089958
- WAY 100635 maleate
- 3YQY8P5QGX
- C25H34N4O2
- MFCD00916243
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