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ESTRADIOL BENZOATE
SynDRA canonical compound SYN0001685 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ESR1 |
|---|
| Mechanism of action | contraceptive agent |
|---|
All known targets
- ESR1
- ADORA3
- ADRA2C
- Ar
- FYN
- HTR2B
- NR3C1
- PGR
- SHBG
- SLC6A2
- SLC6A4
- ESR2
Mechanisms of action (all sources)
- ESR1 AGONIST
- ESR1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- MC4R
- MC3R
- MBNL1
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KMT2A
- KCNH2
- HTT
- HTR6
- HTR2C
- HTR2A
- HSPA5
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- MC5R
- MMP1
- MMP9
- PTGS2
- USP1
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMN1
- SLC6A3
- SIGMAR1
- PTPRC
- PTGS1
- NFE2L2
- PTAFR
- PRKCA
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP3A7
- GCR
- GEMI
- MDR1
- MLP3A
Drug classes
- Estrogen Receptor Agonists
- Estrogens
- Hormones
- Estrogen
- Contraceptive Agents, Hormonal
- contraceptive agent
- Contraceptive Agents
- Contraceptive Agents, Female
- Reproductive Control Agents
ATC classes
- L02A · HORMONES AND RELATED AGENTS
- G03C · ESTROGENS
- HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- HYPOTHALAMIC HORMONES
Cross-references
Synonyms
- benzhormovarine
- benzoestrofol
- benzofoline
- dimenformon benzoate
- estradiol monobenzoate
- Benzoate d'estradiol
- Benzoato de estradiol
- Estradiol 3-benzoate
- NSC-9566
- Benztrone
- Progynon b oleoso
- estradiol.benzoate
- Benzhormovarine
- Benzoestrofol
- Benovocylin
- Oestradiol benzoate
- Estradiol monobenzoate
- Benzofoline
- Follidrin
- Ovasterol-B
- Benzo-Gynoestryl
- Primogyn B
- Progynon-B
- Progynon benzoate
- Eston-B
- Diffollisterol
- Difolliculine
- Femestrone
- Follicormon
- Gynecormone
- Gynformone
- Hidroestron
- Hormogynon
- Unistradiol
- Graafina
- Solestro
- Dimenformon benzoate
- De graafina
Reported adverse events
- Dementia
- Endometrial cancer
- Cardiovascular disorder
- DVT
- Cancer
- TIA
- UTI
- Breast cancer
- Headache
- Hirsutism
- Urticaria
- Erythema
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