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NICORANDIL
SynDRA canonical compound SYN0001631 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ABCC9 | KCNJ11 | KCNJ8 |
|---|
| Mechanism of action | nitric oxide donor | potassium channel activator |
|---|
| Indication | angina pectoris |
|---|
| Disease area | cardiology |
|---|
All known targets
- KCNJ11
- ABCC9
- KCNJ1
- KCNJ8
- NPR1
Mechanisms of action (all sources)
- KCNJ11 MODULATOR
- nitric oxide donor
- potassium channel activator
- ABCC9 ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- ADORA2A
- HDAC6
- HRH1
- HRH2
- HRH3
- HSD17B10
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- GMNN
- GHSR
- EHMT2
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- ACM5
- CP2C9
- CP2CJ
- KCJ11
Drug classes
- Anti-Arrhythmia Agents
- Antihypertensive Agents
- Cardiovascular Agents
- Micronutrients
- Vasodilator Agents
- Vitamin B Complex
- Vitamins
ATC classes
- C01D · VASODILATORS USED IN CARDIAC DISEASES
Cross-references
Synonyms
- perisalol
- sigmart
- Sigmart
- SG-75
- Ikorel
- Adancor
- Dancor
- Nicorandilum
- Aventis Brand of Nicorandil
- Aventis Pharma Brand of Nicorandil
- Merck Brand of Nicorandil
- Merck Lipha Sante Brand of Nicorandil
- Nicorandil Aventis Brand
- Nicorandil Merck Brand
- Rhone-Poulenc Rorer Brand of Nicorandil
- SG75
- Ikorel (TN)
- Nicorandilum [INN-Latin]
- RP-46417
- Sigmart (TN)
- Nitrate, 2-Nicotinamidethyl
- Nitrate, 2-Nicotinamidoethyl
- N-(2-Hydroxyethyl)nicotinamide nitrate
- Nicorandil (JP15/USAN/INN)
- Nicorandil [USAN:BAN:INN:JAN]
- N-(2-Hydroxyethyl)nicotinamide nitrate (ester)
- N-[2-(Nitrooxy)ethyl]pyridine-3-carboxamide
- 2-Nicotinamidethyl Nitrate
- 2-Nicotinamidoethyl nitrate
- 2-(Nicotinamido)ethyl nitrat
- 2-(Pyridine-3-carboxamido)ethyl Nitrate
- 2-(pyridine-3-carbonylamino)ethyl nitrate
- 2-[(pyridin-3-ylcarbonyl)amino]ethylnitrat
- SG 75
- 2-(nicotinamido)ethyl nitrate
- CHEBI:31905
- N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE
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