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PROADIFEN
SynDRA canonical compound SYN0001572 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | NOS1 |
|---|
| Mechanism of action | Nitric oxide synthase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Nitric oxide synthase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SIGMAR1
- NR1I2
- ABCB11
- PMP22
- LMNA
- MPHOSPH8
- MTOR
- NFKB1
- NPSR1
- RAB9A
- KCNH2
- SAMHD1
- SLCO1B1
- SLCO1B3
- TDP1
- TSHR
- KDM4E
- IDH1
- ALOX15B
- CYP2C19
- ARSA
- ATAD5
- ATXN2
- BLM
- CBX1
- CYP1A2
- CYP2C9
- HSD17B10
- CYP2D6
- CYP3A4
- EHMT2
- GLP1R
- GMNN
- HDAC6
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- ACM5
- SCN3A
- SCN2A
- SCN1A
- RARA
- NSD2
- NPR2
- MDR1
- JUN
- GPR32
- ESRRA
- DRD2
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- ANDR
- TP53
Drug classes
Cross-references
Synonyms
- Proadifene
- Proadifeno
- Proadifenum
- Propyladiphenin
- A510CA4CBT
- RefChem:176093
- DTXCID8028426
- Acetate, Diethylaminoethyldiphenylpropyl
- Diethylaminoethyldiphenylpropyl Acetate
- Ethyl aprofen
- Proadifen [INN]
- 2-(Diethylamino)ethyl 2,2-diphenylpentanoate
- HL 8727
- 2-Diethylaminoethyl propyldiphenylacetate
- 2-Diethylaminoethyl-2,2-diphenylvalerate
- ACETIC ACID, PROPYLDIPHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER
- AV 54315
- Valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethyl ester
- Proadifene [INN-French]
- Proadifenum [INN-Latin]
- Proadifeno [INN-Spanish]
- NSC39690
- CCRIS 7248
- NSC170997
- CAS-62-68-0
- UNII-A510CA4CBT
- BRN 2478573
- AI3-22951
- 2-(Diethylamino)ethyl 2,2-diphenylvalerate hydrochloride
- 2,2-Diphenylpentansaeure-2-diethylaminoethylester
- Spectrum_001487
- 2-diethylaminoethyl 2,2-diphenylpentanoate
- Prestwick0_000778
- Prestwick1_000778
- Prestwick2_000778
- Prestwick3_000778
- Spectrum2_000924
- Spectrum3_001172
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