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MEDROXYPROGESTERONE ACETATE
SynDRA canonical compound SYN0001553 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | progesterone receptor agonist |
|---|
| Indication | contraceptive |
|---|
| Disease area | endocrinology |
|---|
All known targets
- PGR
- ESR1
- AKR1C1
- AKR1C2
- AKR1C3
- AR
- Ar
- CYP2C19
- ESR2
- HRH2
- NR3C1
- NR3C2
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- MAPK1
- NR1H4
- NPY2R
- NPY1R
- NPSR1
- NFE2L2
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- ABCB11
- OPRD1
- LMNA
- LCK
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH1
- HMGCR
- HDAC6
- MAOA
- OPRK1
- ABCC4
- SIGMAR1
- VDR
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CFTR
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- ESRRA
- GCR
- GLI3
- JUN
- KSYK
- NF2L2
- NSD2
- PRKN
- RARA
- SYK
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral, Hormonal
- Contraceptives, Oral, Synthetic
- Reproductive Control Agents
- Progestin
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Contraceptive Agents, Male
ATC classes
- L02A · HORMONES AND RELATED AGENTS
- G03A · HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- G03D · PROGESTOGENS
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- AMEN
- CURRETAB
- CYCRIN
- DEPO-PROVERA
- DEPO-SUBQ PROVERA 104
- Depo-Provera
- LUNELLE
- PREMPHASE (PREMARIN;CYCRIN 14/14)
- PREMPHASE 14/14
- PREMPRO
- PREMPRO (PREMARIN;CYCRIN)
- medroxyprogesterone
- medoxyprogesterone
- medroxyprogesteron
- depomedroxyprogesterone acetate
- medroprogesterone acetate
- hysron
- Medroxyprogesterone
- Medroxiprogesterona
- Medroxyprogesterone 17-acetate
- Depot-medroxyprogesterone acetate
- Farlutal inyectable
- Medroxyprogesteroni acetas
- G03AC06
- NSC-21171
- NSC-26386
- NSC-27408
- TV-46046
- Adgyn medro
- Amen
- Climanor
- Curretab
- Cycrin
- Depo-progevera
- Depo-provera
- Depo-provera oncology
- Depo-subq provera 104
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