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FINASTERIDE
SynDRA canonical compound SYN0001526 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SRD5A2 |
|---|
| Mechanism of action | 5 alpha reductase inhibitor |
|---|
| Indication | androgenetic alopecia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- SRD5A2
- SRD5A1
- AKR1D1
- AR
- CYP2C19
- CYP2C9
- HSD3B1
- SRD5A3
- Srd5a1
- Srd5a2
Mechanisms of action (all sources)
- 5 alpha reductase inhibitor
- SRD5A2 INHIBITOR
- Steroid 5-alpha-reductase 2 inhibitor
- SRD5A1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR1
- KDR
- NFKB1
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- ABCB11
- NPY1R
- HTR7
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B7
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- KCNH2
- NPY2R
- GIPR
- PTGS2
- THPO
- TDP1
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP2CJ
- ESRRA
- GLI3
- NF2L2
- NR1H4
- RARA
Drug classes
- 5-alpha Reductase Inhibitors
- 5-alpha Reductase Inhibitor
- Enzyme Inhibitors
- Hormone Antagonists
- Steroid Synthesis Inhibitors
- Urological Agents
ATC classes
- G04C · DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
Cross-references
Synonyms
- ENTADFI
- Entadfi
- FINASTERIDE AND TADALAFIL
- PROPECIA
- PROSCAR
- Propecia
- Proscar
- finastid
- prosteride
- prostide
- propecia
- Finasterida
- MK-906
- NSC-741485
- NSC-759318
- Aindeem
- Finasteride component of entadfi
- Prostide
- Andozac
- Eucoprost
- FIT
- Finasteridum
- Finastid
- Finpecia
- Propeshia
- Cahill May Roberts Brand of Finasteride
- Chibro-Proscar
- Frosst Iberica Brand of Finasteride
- Lipha Brand of Finasteride
- MSD Brand of Finasteride
- MSD Chibropharm Brand of Finasteride
- MK-0906
- MK906
- Merck Brand 1 of Finasteride
- Merck Brand 2 of Finasteride
- Merck Frosst Brand 1 of Finasteride
- Merck Frosst Brand 2 of Finasteride
Reported adverse events
- Rash
- Asthenia
- Dizziness
- Headache
- Hypotension
- Rhinitis
- Somnolence
- Hypersensitivity
- Breast disorder
- Libido decreased
- Back pain
- Dyspepsia
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