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URAPIDIL
SynDRA canonical compound SYN0001514 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR1A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- HTR1A
- ADRA1A
- ADRA1B
- ADRA1D
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- HTR1A AGONIST
- ADRA1A ANTAGONIST
- ADRA1D ANTAGONIST
- ADRA1B ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- ADRA2C
- PDE3A
- DRD2
- ADRB2
- ADRB1
- DRD3
- ADRA2B
- SLC6A4
- HRH3
- HTR2A
- HTR2B
- MLNR
- HTR2C
- HTR3A
- KCNH2
- HRH2
- LMNA
- MAOA
- MAPK1
- MAPT
- MC3R
- ABCB11
- NPY1R
- NR1I2
- NR3C1
- HDAC6
- OPRK1
- OPRM1
- PDE4D
- PGR
- PMP22
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- TBXA2R
- OPRD1
- ESR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- CP2C9
- CP2CJ
- CP2D6
- HTT
- ITA4
Drug classes
- Adrenergic Agents
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Antihypertensive Agents
- Cardiovascular Agents
- Neurotransmitter Agents
- Serotonin Agents
- Serotonin Receptor Agonists
- Vasodilator Agents
ATC classes
- C02C · ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Cross-references
Synonyms
- ebrantil
- eupressyl
- mediatensyl
- uraprene
- uropidil
- urapidil hydrochloride
- urapidil HCl
- Ebrantil
- NSC-310405
- Eupressyl
- Mediatensyl
- Uraprene
- Urapidilum [INN-Latin]
- UNII-A78GF17HJS
- NSC 310405
- B-66256
- C20H29N5O3
- EINECS 252-130-4
- BRN 0725782
- A78GF17HJS
- MLS003115907
- 6-(3-(4-(o-Methoxyphenyl)-1-piperazinyl)propylamino)-1,3-dimethyluracil
- 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil
- NCGC00016066-07
- Ebrantil (TN)
- 6-((3-(4-(o-Methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyluracil
- W-106718
- Urapidilum
- urapidil(jan)
- TgAAV-TNFR:Fc
- DTXCID501425
- RefChem:933840
- C02CA06
- B 66256
- MFCD00133908
- CAS-64887-14-5
- Urapidil [INN:BAN:JAN]
- Urapidil (Standard)
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