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INDORAMIN
SynDRA canonical compound SYN0001513 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA1A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | benign prostatic hyperplasia (BPH) | hypertension |
|---|
| Disease area | cardiology | urology |
|---|
All known targets
- ADRA1D
- ADRA1A
- ADRA1B
- ADRA2B
- ADRA2C
- ADRA2A
- Adra1a
- Adra1b
- Adra1d
- Adra2a
- Adra2b
- Adra2c
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRA1A ANTAGONIST
- ADRA1B ANTAGONIST
- ADRA1D ANTAGONIST
- ADRA1D INHIBITOR
- ADRA2C INHIBITOR
- ADRA2B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- BAZ2B
- CYP1A2
- CYP2B6
- CYP2C19
- CYP2C8
- CYP2C9
- CYP2D6
- CYP3A4
- GLP1R
- HDAC6
- POLK
- PTH1R
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ADA1A
- ADA1B
- ADA1D
- ADRB2
- AHR
- ANDR
- CP2D6
- DRD1
- DRD2
- DRD3
- GLI3
- KCNH2
Drug classes
- Adrenergic Agents
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Antihypertensive Agents
- Cardiovascular Agents
- Neurotransmitter Agents
ATC classes
- C02C · ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Cross-references
Synonyms
- Wy21901
- Wy-21901
- indoramine
- Indoramine
- Indoramina
- WY-21901
- Baratol
- Doralese tiltab
- WY 21901
- Indoraminum [INN-Latin]
- Indoramine [INN-French]
- Indoramina [INN-Spanish]
- UNII-0Z802HMY7H
- EINECS 248-041-5
- BRN 0494035
- 0Z802HMY7H
- CHEMBL279516
- C22H25N3O
- Benzamide, N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)-
- 3-(2-(4-Benzamidopiperid-1-yl)ethyl)indole
- JXZZEXZZKAWDSP-UHFFFAOYSA-N
- N-(1-(2-Indol-3-ylethyl)-4-piperidyl)benzamide
- N-(1-(2-(1H-Indol-3-yl)ethyl)-4-piperidinyl)benzamide
- Benzamide, N-(1-(2-indol-3-ylethyl)-4-piperidyl)-
- Benzamide, N
- Indoraminum
- N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide
- N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide
- Benzamide, N-[1-[2-(1H-indol-3-yl)ethyl]-4-piperidinyl]-
- N-(1-(2-(1H-indol-3-yl)ethyl)piperidin-4-yl)benzamide
- RefChem:790998
- DTXCID3028344
- C02CA02
- Doralese
- Indoramine;Wy 21901
- N-[1-[2-(1H-indol-3-yl)ethyl]-4-piperidinyl]benzamide
- 3-[2-(4-Benzamido-1-piperidyl)ethyl]indole
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