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ALITRETINOIN
SynDRA canonical compound SYN0001505 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | RXRG |
|---|
| Mechanism of action | Retinoid receptor agonist |
|---|
All known targets
- RARA
- RARB
- RARG
- RXRA
- RXRB
- RXRG
- NR1H2
- NR1H3
- NR4A1
- RORC
- Rara
- Rarb
Mechanisms of action (all sources)
- Retinoid receptor agonist
- RXRB AGONIST
- RARG AGONIST
- RXRG AGONIST
- RARB AGONIST
- RARA AGONIST
- RXRA AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- PPARG
- ACHE
- PPARA
- MAPT
- OPRM1
- PDE3A
- PDE4A
- PGR
- PPARD
- KDR
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TDP1
- MAOA
- HTR2B
- ADORA1
- CHRM1
- ADORA3
- ADRA1A
- ADRA2A
- ALDH1A1
- APEX1
- AR
- CHRM2
- HTR1A
- CRABP2
- DRD1
- DRD3
- EHMT2
- F2
- HRH3
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2CJ
- CP3A4
- CSTA
- GCR
- GLI3
- NF2L2
- NR1I2
- NR1I3
- NR2C2
- NR2F6
- TSHR
- VKOR1
Drug classes
- Antineoplastic Agents
- Dermatologic Agents
- Retinoid
ATC classes
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- PANRETIN
- Panretin
- panrexin
- panretyn
- panretin
- 9-cis-retinoic acid
- Alitretinoine
- Alitretinoina
- Retinoic acid 9-cis-form
- AGN-192013
- AGN192013
- ALRT-1057
- ALRT1057
- BAL-4079
- LG-100057
- LG100057
- LGD-1057
- LGD1057
- NSC-659772
- Toctino
- 9-Cis-Retinoic Acid
- 1UA8E65KDZ
- isotretinoin impurity d (ep impurity)
- ALRT 1057
- Retinoic acid 9-cis-
- tretinoin impurity d (ep impurity)
- NSC 659772
- 9-cis-Tretinoin
- Panrexin
- Panretyn
- Panretin Gel
- 9(Z)-Retinoic acid
- retinoic acid, 9-cis
- alitretinoina
- alitretinoine
- alitretinoinum
- Atragen
- Effederm
Reported adverse events
- Pain
- Pruritus
- Rash
- Erythema
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