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ETHOSUXIMIDE
SynDRA canonical compound SYN0001460 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CACNA1G |
|---|
| Mechanism of action | Succinimide antiepileptic |
|---|
| Indication | epilepsy |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- CACNA1H BLOCKER
- Voltage-gated T-type calcium channel blocker
- CACNA1G BLOCKER
- CACNA1I BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- MAOB
- NPY1R
- NPSR1
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- NR1I2
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- NPY2R
- NR3C1
- GHSR
- SAMHD1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- Anti-epileptic Agent
- Succinimide antiepileptic
ATC classes
Cross-references
Synonyms
- ZARONTIN
- Zarontin
- ethosuxide
- etosuximid
- 3-Methyl-3-ethylsuccinimide
- Etosuximida
- Ethosuximidum
- Pyknolepsinum
- CI-366
- CN-10,395
- CN-10395
- NSC-64013
- PM-671
- Emeside
- Suxinutin
- Aethosuccimidum
- Aethosuximide
- Asamid
- Atysmal
- Capitus
- Ethosuccimid
- Ethosuccimide
- Ethosuccinimide
- Ethosuxide
- Ethylmethylsuccimide
- Ethymal
- Etomal
- Etosuccimide
- Etosuximid
- Etosuximide
- Mesentol
- Pemal
- Pemalin
- Pentinimid
- Peptinimid
- Petinimid
- Petnidan
Reported adverse events
- Stevens-Johnson syndrome
- Eosinophilia
- Myopia
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