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FURAMIDINE
SynDRA canonical compound SYN0001444 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PRMT1 |
|---|
| Mechanism of action | protein arginine N-methyltransferase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- protein arginine N-methyltransferase inhibitor
- DNA synthesis inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TOP1
- TDP1
- NQO2
- CASP1
- PRMT5
- POLK
- POLI
- HSD17B10
- HPGD
- ALDH1A1
- FEN1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CASP7
- HDAC6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
Cross-references
Synonyms
- DB-75
- DB75
- NSC-305831
- 2,5-Bis(4-amidinophenyl)furan
- Benzenecarboximidamide, 4,4'-(2,5-furandiyl)bis-
- DB 75
- 2,5-BAPF
- WR-199385
- RefChem:141734
- DTXCID00146755
- 2,5-bis(4-guanylphenyl)furan
- Furamidine Dihydrochloride
- DB75;NSC 305831
- 4,4'-(Furan-2,5-diyl)dibenzimidamide
- NSC305831
- 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- BRN 1435532
- Furandiamidine
- Furamidine dihydrochloride?
- UNII-08GH1YF0RA
- NCIStruc1_001694
- NCIStruc2_001468
- 5-18-07-00177 (Beilstein Handbook Reference)
- SCHEMBL549198
- orb1709656
- 2,5-Bis(4-amidinophenyl)-furan
- LNA78681
- BDBM50388602
- CCG-37385
- NCGC00014688
- NCI305831
- AKOS030254780
- HY-110137A
- NCGC00014688-02
- NCGC00014688-03
- NCGC00014688-06
- NCGC00097791-01
- NCGC00097791-02
- NCI60_002601
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