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PURVALANOLA
SynDRA canonical compound SYN0001435 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CDK1 |
|---|
| Mechanism of action | DYRK inhibitor |
|---|
All known targets
- CDK1
- CDK2
- CDK5
- IRF3
- CDK4
- SYK
- SRC
- SIRT1
- RPS6KA1
- PTGS2
- ATP5F1A
- CSNK1G3
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- DYRK inhibitor
- SYK INHIBITOR
- IRF3 INHIBITOR
- CDK1 INHIBITOR
- CDK2 INHIBITOR
- CCNA2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PRKACA
- INSR
- GPR183
- SLC6A2
- FPR3
- FPR1
- HTR1D
- PAK4
- HTR2B
- GPR65
- HTR5A
- HTR6
- TMEM97
- MAPK3
- HTR2C
- GPR35
- DRD4
- DYRK1A
- TSPO
- NUAK1
- PLK1
- NEK2
- PKN2
- NEK3
- NEK6
- NEK7
- NLK
- PIM3
- NTRK1
- PIM2
- NTRK2
- PASK
- OPRD1
- OPRM1
- PAK2
- PAK3
- PIM1
- PHKG2
- PAK5
- PDPK1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNA1
- CCNB1
- CCNB2
- CCNB3
- CCNE2
- CDK5R1
- CP1A2
- CP2C9
- CP3A4
- IFNB1
- IFNG
- KSYK
- NSD2
- PRKACB
- PRKACG
Cross-references
Synonyms
- Piceatannol
- Purvalanol A
- AC1L1JD0
- IN1131
- 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropyl-purine
- SCHEMBL3311119
- GTPL6030
- CTK8F1120
- CHEBI:93781
- HMS3229M14
- KS-00001DB0
- HSCI1_000128
- AKOS030238850
- CCG-206875
- RT-015158
- K00014
- 2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
- 3-Hydroxyresveratol
- piceatanol
- astringinin
- 3,5,3',4'-Tetrahydroxystilbene
- (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol
- 3,3',4'5-Tetrahydroxystilbene
- 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
- 3,3',4,5'-Tetrahydroxystilbene
- UNII-6KS3LS0D4F
- NSC-365798
- NSC 622471
- 6KS3LS0D4F
- CHEMBL69863
- 3,3',4,5'-Stilbenetetrol
- 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol
- CHEBI:28814
- C14H12O4
- NSC365798
- NSC622471
- 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-
- purvalanol-a
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