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BETULIN

SynDRA canonical compound SYN0001428 — structure-anchored drug synonym record

All known targets

• PYGM
• SOAT1

Mechanisms of action (all sources)

• ACAT inhibitor
• sterol regulatory element binding protein (SREBP) inhibitor
• PYGM INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PTPN1
• RELA
• CDC42
• GPBAR1
• HDAC6
• NT5E
• PTGS2
• RAC1
• RHOA
• SLCO1B1
• SLCO1B3
• TOP1
• TOP2A

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• TP53

Cross-references

• PubChem CID: 72326
• ChEMBL: CHEMBL23236
• DrugBank: DB16890
• ChEBI: 3086
• KEGG: C08618
• RxNorm: 2467840
• Wikipedia: Betulin
• TTD: D05KJY
• LINCS BRD: BRD-K64874225

Synonyms

• Betulinol
• Betuline
• Trochol
• Lup-20(29)-ene-3b,28-diol
• Betulol
• Lup-20(29)-ene-3beta,28-diol
• UNII-6W70HN7X7O
• NSC 4644
• C30H50O2
• EINECS 207-475-5
• Lup-20(30)-ene-3beta,28-diol
• AI3-62999
• CHEBI:3086
• 6W70HN7X7O
• Lup-20(29)-ene-3,28-diol, (3beta)-
• (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(Hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol
• Betulinic alcohol
• lup-20(29)-ene-3 beta,28-diol
• NSC-4644
• (+)-betulin
• ORISTRACT BTL
• CP BETULIN
• RefChem:568020
• DTXCID801477793
• lup-20(29)-ene-3,28-diol, 3,28-diacetate, (3 beta)-
• MFCD00016802
• (3beta)-lup-20(29)-ene-3,28-diol
• Lup-20(29)-ene-3,28-diol, (3.beta.)-
• SR-05000002167
• NSC4644
• Botulin
• NSC692218
• Lup-20(29)-ene-3.beta.,28-diol
• Lup-20(30)-ene-3.beta.,28-diol
• Betulin (Standard)
• Betulinol (obsol.)
• Betulin, 23
• Betulin, >=98%