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L-732138
SynDRA canonical compound SYN0001426 — structure-anchored drug synonym record
| Primary target(s) | TACR1 |
|---|
| Mechanism of action | Tachykinin antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Tachykinin antagonist
- TACR1 ANTAGONIST
- TACR1 INHIBITOR
- TACR2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- MAPT
- TP53
- THPO
- TARDBP
- TACR3
- SMAD3
- RAPGEF4
- PTH1R
- POLK
- POLI
- POLB
- PIN1
- NPSR1
- NFKB1
- MPHOSPH8
- LMNA
- APEX1
- KDM4E
- KDM4A
- KCNH2
- GLP1R
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CISD1
- CBX1
- BLM
- ARSA
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADA10
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- RPGF4
- UBP1
Cross-references
Synonyms
- L 732138
- L-732,138
- 3,5-Bis(tfm)Bz nactrp
- 3,5-Bis(trifluoromethyl)benzyl N-acetyltryptophan
- N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester
- CHEMBL22870
- N-Acetyl-L-trp-3,5-bistrifluoromethylbenzyl ester
- L732138
- N-Acetyl-L-tryptophan-3,5-bistrifluoromethylbenzyl ester
- N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester
- [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate
- AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER
- L-Tryptophan, N-acetyl-, (3,5-
- RefChem:924363
- 3,5-bis(trifluoromethyl)benzyl acetyl-L-tryptophanate
- MFCD00237267
- C22H18F6N2O3
- BYYQYXVAWXAYQC-IBGZPJMESA-N
- Tocris-0868
- Lopac-A-5330
- Lopac0_000028
- MLS002172463
- BIDD:GT0377
- 3,5-bis(trifluoromethyl)benzylacetyl-l-tryptophanate
- GTPL9461
- orb1299099
- SCHEMBL3682000
- SCHEMBL29374396
- BDBM21016
- GLXC-15006
- HMS2234A11
- HMS3260E17
- Tox21_500028
- AKOS015898307
- CCG-204124
- LP00028
- SDCCGSBI-0050017.P002
- EBC-8109290
- NCGC00015066-01
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