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FLUFENAMIC ACID
SynDRA canonical compound SYN0001393 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | AKR1C3 |
|---|
| Mechanism of action | Chloride channel antagonist |
|---|
All known targets
- PTGS2
- AKR1C3
- PTGS1
- AR
- TRPM5
- PKD2L1
- TRPM2
- GJD2
- KCNT2
- GJC3
- GJD3
- GJD4
Mechanisms of action (all sources)
- Chloride channel antagonist
- ANO1 INHIBITOR
- GJE1 MODULATOR
- GJB7 MODULATOR
- GJB2 MODULATOR
- GJB6 MODULATOR
- GJC3 MODULATOR
- GJB4 MODULATOR
- GJB3 MODULATOR
- GJB5 MODULATOR
- GJD3 MODULATOR
- GJB1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM3
- DRD3
- HRH1
- ADRA1A
- CHRM1
- HTR2A
- HTR2C
- NR3C1
- NPY2R
- NPY1R
- MT-CO2
- MLNR
- MC4R
- MC3R
- MBNL1
- ADORA1
- MAPT
- NTSR1
- LMNA
- KCNK18
- KCNH2
- HTR3A
- HTR2B
- HTR1A
- HSPA5
- HRH3
- MAOA
- OPRK1
- OPRD1
- SLC6A4
- TSHR
- TRPV1
- TEAD2
- TDP1
- TBXA2R
- TARDBP
- SNCA
- SMN1
- SLCO1B3
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABCB6
- CP1A2
- TERA
- RPGF4
- RAPGEF4
- PRGR
- PPARG
- PK2L1
- PHGDH
- NR1I2
- NF2L2
- MDR1
- IP6K1
- IFNG
- HDAC9
- GCR
- ESRRA
- CP3A7
- CP2C9
- TP53
Drug classes
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- fluphenamic acid
- Acide flufenamique
- Acido flufenamico
- Flufenamate
- CI-440
- CN-27,554
- CN-27554
- INF-1837
- NSC-219007
- NSC-82699
- Arlef
- Meralen
- Fluphenamic acid
- Nichisedan
- Achless
- Tecramine
- Paraflu
- Lanceat
- Flufacid
- Plostene
- Fullsafe
- Parlef
- Surika
- Parlif
- Flufenaminsaeure
- Reumajust A
- N-(3-Trifluoromethylphenyl)anthranilic acid
- Ristogen
- Sastridex
- Ansatin
- 2-((3-(Trifluoromethyl)phenyl)amino)benzoic acid
- Fluore-200
- 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid
- ANT-1
- Acidum flufenamicum
- TVX 916
- INF 1837
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