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MEBENDAZOLE
SynDRA canonical compound SYN0001387 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TUBA1A | TUBB | TUBB4B |
|---|
| Mechanism of action | tubulin polymerization inhibitor |
|---|
| Indication | ascariasis | hookworm | pinworm | whipworm |
|---|
| Disease area | infectious disease |
|---|
All known targets
- ABL1
- CDPK1
- KDR
- TUBA1A
- TUBB
- TUBB4B
Mechanisms of action (all sources)
- tubulin polymerization inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR2
- LMNA
- MMP9
- MMP1
- MLNR
- METAP2
- METAP1
- MDH1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- ABCB1
- NPY1R
- KCNH2
- HTT
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- HMBS
- LCK
- NPY2R
- HDAC6
- NR3C1
- USP2
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- ANDR
- TP53
- SYK
- STK33
- SMAD3
- SMAD2
- PPARG
- PARP1
- NTMT1
- NTM1A
- NSD2
- NR1H4
- NF2L2
- MDR1
- MAPK10
- KSYK
- IFNG
- HTR1E
- HDAC9
- GEMI
- ESRRA
- CREB1
- CP1A2
- ATAD5
- YAP1
Drug classes
- Anthelmintic
- Anthelmintics
- Anti-Infective Agents
- Antimitotic Agents
- Antinematodal Agents
- Antiparasitic Agents
- Tubulin Modulators
ATC classes
- P02C · ANTINEMATODAL AGENTS
Cross-references
Synonyms
- EMVERM
- Emverm
- VERMOX
- Vermox
- vermox
- Mebendazol
- Mebendazolum
- Ovitelmin
- Pantelmin
- Vermicidin
- Zhihuanqing
- NSC-184849
- R 17,635
- R-17635
- Mebenvet
- Telmintic
- Mebendazole polymorph c
- Bantenol
- Banworm
- Besantin
- Lomper
- MBDZ
- Madicure
- Mebendan
- Mebenoazole
- Mebex
- Mebutar
- Noverme
- Sqworm
- Sufil
- Surfont
- Telmin
- Vermicol
- Vermidil
- Vermin
- Vermirax
- Verpanyl
- Versid
Reported adverse events
- Neutropenia
- Alopecia
- Angioedema
- Dizziness
- Flatulence
- Hepatitis
- Hypersensitivity
- Nausea
- Urticaria
- Vomiting
- Agranulocytosis
- Rash
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