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CLOFIBRIC ACID
SynDRA canonical compound SYN0001379 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
| Indication | hyperlipidemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARA AGONIST
- Platelet aggregation inhibitor
- Lipase clearing factor inhibitor
- Peroxisome proliferator-activated receptor alpha agonist
- LPL ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PPARG
- ACHE
- MC3R
- PDE3A
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MAPT
- PDE5A
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- PDE4A
- PGR
- ADORA1
- SLCO1B3
- USP1
- UGT2B7
- UGT2B4
- UGT2B10
- UGT1A8
- THRB
- TDP1
- TBXAS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antimetabolites
- Anticholesteremic Agents
- Hypolipidemic Agents
- Lipid Regulating Agents
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Peripheral Nervous System Agents
- Respiratory System Agents
- Antioxidants
- Protective Agents
- Radiation-Sensitizing Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
Cross-references
Synonyms
- chlorfibrinic acid
- chlorofibrinic acid
- chlorophibrinic acid
- clofibrilic acid
- clofibrin
- clofibrinic acid
- aluminium clofibrate
- Acide clofibrique
- Acido clofibrico
- NSC-1149
- Fibrates
- 2-(4-Chlorophenoxy)-2-methylpropanoic acid
- Chlorofibrinic acid
- Clofibrinic acid
- Chlorfibrinic acid
- Clofibrin
- 2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID
- Chlorophibrinic acid
- PCIB
- Clofibrate free acid
- Clofibrinsaeure
- Regulipid
- Regadrin
- PCPIB
- 2-(p-Chlorophenoxy)-2-methylpropionic acid
- 2-(4-Chlorophenoxy)isobutyric Acid
- 4-CPIB
- 2-(p-Chlorophenoxy)isobutyric acid
- Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-
- alpha-(p-Chlorophenoxy)isobutyric acid
- Acidum c
- clofibric-acid
- NSC 1149
- Acidum clofibricum
- p-Chlorophenoxyisobutyric Acid
- Acide (p-chlorophenoxy)-2 methyl-2 propionique
- alpha-(4-Chlorophenoxy)-alpha-methylpropionic acid
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