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ETOMIDATE
SynDRA canonical compound SYN0001371 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | Membrane permeability inhibitor |
|---|
| Indication | general anaesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GABRB2
- GABRA1
- GABRA2
- GABRG2
- GABRG3
- GABRQ
- GABRA3
- GABRA4
- GABRA5
- GABRA6
- GABRB1
- GABRP
Mechanisms of action (all sources)
- GABA receptor modulator
- Membrane integrity inhibitor
- Membrane permeability inhibitor
- GABRA1 POSITIVE MODULATOR
- GABRB2 POSITIVE MODULATOR
- GABRG2 POSITIVE MODULATOR
- GABRB3 POSITIVE MODULATOR
- GABRA4 POSITIVE MODULATOR
- GABRG3 POSITIVE MODULATOR
- GABRQ POSITIVE MODULATOR
- GABRA3 POSITIVE MODULATOR
- GABRP POSITIVE MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- ADORA1
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SMPD1
- HRH3
- HRH2
- HRH1
- CCKAR
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
Drug classes
- Anesthetics
- Anesthetics, Intravenous
- Central Nervous System Agents
- Central Nervous System Depressants
- Hypnotics and Sedatives
- General Anesthetic
ATC classes
- N01A · ANESTHETICS, GENERAL
Cross-references
Synonyms
- (+)-Etomidate
- amidate
- D-Etomidate
- hypnomidate
- Etomidato
- Hypnomidate
- NSC-759160
- Amidate
- Absele
- Ethnor
- Ethomidate
- Etomidatum
- Radenarcon
- Radenarkon
- Etomidic acid
- R 16659
- R-26490
- R26490
- Amidate (TN)
- Amidate (pharmaceutical)
- Amidate, Etomidate
- Etomidato [INN-Spanish]
- Etomidatum [INN-Latin]
- Etomidate (USAN/INN)
- Etomidate [USAN:BAN:INN]
- Ethyl 3-(1-phenylethyl)imidazole-4-carboxylate
- Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
- R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
- (+)-Ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate
- (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester
- (d)-Etomidate
- 1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
- 1-(1-Phenylethyl)-imidazole-5-carboxylic acid, ethyl ester
- 1-(alpha-Methylbenzyl)-1H-imidazole-5-carboxylic acid ethyl ester
- 1H-Imidazole-5-carboxylic acid, 1-((1R)-1-phenylethyl)-, ethyl ester
- 3-(1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester
- etomidate (ep monograph)
- Z22628B598
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