← SynDRA

LEVONORDEFRIN

SynDRA canonical compound SYN0001360 — structure-anchored drug synonym record

All known targets

• ADRA2B
• ADRA2C
• ADRA1D
• ADRA2A
• ADRA1A
• ADRA1B
• Adra1a
• Adra1b
• Adra1d
• Adra2a
• Adra2b
• Adra2c

Mechanisms of action (all sources)

• ADRA2A AGONIST
• Adrenergic receptor alpha-2 agonist
• ADRA2C AGONIST
• ADRA2B AGONIST
• TADA2A AGONIST
• ADRA1D INHIBITOR
• ADRA1B INHIBITOR
• ADRA1A INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ALOX15
• KDM4E
• TSHR
• THPO
• TDP1
• SLCO1B3
• SLCO1B1
• SAMHD1
• RECQL
• POLK
• NFKB1
• LMNA
• HSD17B10
• ALOX15B
• HIF1A
• HDAC6
• EHMT2
• CYP3A4
• CYP2D6
• CYP2C9
• CYP2C19
• CYP1A2
• ATXN2
• APEX1
• VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ACES
• ADA1D
• ADRB2
• G3P
• GLI3
• GNRHR
• GPR151
• LOX15
• MITF
• NTM1A
• NTMT1
• PE2R2
• PPM1D

Drug classes

• Cardiovascular Agents
• Vasoconstrictor Agents
• vasodilator

Cross-references

• PubChem CID: 164739
• ChEMBL: CHEMBL677
• DrugBank: DB06707
• ChEBI: CHEBI:141146
• KEGG: D02388
• RxNorm: 132889
• Wikipedia: Corbadrine
• TTD: D0E9VU

Synonyms

• ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN
• CARBOCAINE W/ NEO-COBEFRIN
• ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN
• MEPIVACAINE HYDROCHLORIDE W/ LEVONORDEFRIN
• POLOCAINE W/ LEVONORDEFRIN
• RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN
• SCANDONEST L
• corbadrine
• (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol
• levoepinefrina
• Corbadrine
• Corbadrina
• Nordefrin (-)-form
• (-)-cobefrin
• L-nordefrin
• L-norephedrine, 3,4-dihydroxy-
• Nordefrin, l-
• BA-2818
• NSC-757084
• Neo-cobefrin
• Neo-Cobefrin
• Nordefrin
• Corbadrinum
• alpha-Methylnoradrenaline
• Corbadrinum [INN-Latin]
• Corbadrina [INN-Spanish]
• L-alpha-Methylnoradrenaline
• Levonordefrin [USP]
• Nordefrin, (-)-
• UNII-V008L6478D
• CHEBI:10304
• Corbadrine (INN)
• Corbadrine [INN]
• Levonordefrin (USP)
• V008L6478D
• CAS-829-74-3
• DSSTox_RID_81553