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FENOFIBRATE
SynDRA canonical compound SYN0001343 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
| Indication | hypercholesterolemia | hypertriglyceridemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- PPARA
- ABCG2
- ACHE
- ADORA3
- ADRB3
- APOA1
- CYP2C19
- CYP2C8
- DRD3
- Fabp1
- HTR2A
- HTR2C
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARA AGONIST
- Peroxisome proliferator-activated receptor alpha agonist
- CLCN1 MODULATOR
- cytochrome P450 inhibitor
- FABP1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ESR1
- CNR1
- MC5R
- MLNR
- MMP1
- MMP9
- MPHOSPH8
- MTOR
- ABCB11
- MC3R
- NFE2L2
- NPSR1
- NPY1R
- NPY2R
- NR3C1
- NTSR1
- MC4R
- MAPK3
- MAPT
- OPRK1
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4A
- KAT2A
- JUN
- HTR6
- HTR3A
- HTR2B
- HTR1A
- HRH3
- OPRD1
- OPRM1
- HRH1
- TBXA2R
- SLCO1B1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- CP19A
- CP1A2
- CP2C9
- CP2CJ
- ESRRA
- FABP2
- GLI3
- NF2L2
- NR1I2
- PRGR
Drug classes
- Peroxisome Proliferator-activated Receptor alpha Agonists
- Antimetabolites
- Hypolipidemic Agents
- Lipid Regulating Agents
- Peroxisome Proliferator Receptor alpha Agonist
- Anticholesteremic Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- ANTARA (MICRONIZED)
- Antara
- FENOFIBRATE (MICRONIZED)
- FENOGLIDE
- Fenoglide
- LIPIDIL
- LIPOFEN
- Lipofen
- TRICOR
- TRICOR (MICRONIZED)
- TRIGLIDE
- clorofibrate
- fenobrate
- lipofene
- procetofen
- procetofene
- Fenofibrato
- Fenofibrate delayed release
- Fenofibrate micronized
- NSC-281319
- Antara (micronized)
- Fenofibrate (micronized)
- Fenogal
- Lipantil
- Lipantil micro 200
- Lipantil micro 267
- Lipantil micro 67
- Lipidil
- Supralip 160
- Tricor (micronized)
- Triglide
- Ankebin
- Controlip
- Durafenat
- Elasterate
- Elasterin
- FNF
Reported adverse events
- Constipation
- Rhinitis
- Cholelithiasis
- Hypersensitivity
- Myopathy
- Pancreatitis
- Photosensitivity reaction
- Urticaria
- Headache
- Nausea
- Rhabdomyolysis
- Hepatotoxicity
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