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ALPRAZOLAM
SynDRA canonical compound SYN0001316 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | Benzodiazepine receptor agonist |
|---|
All known targets
- GABRA1
- GABRA2
- GABRA3
- GABRA5
- GABRB2
- GABRB3
- GABRG2
- GABRG1
- GABRE
- GABRD
- GABRA6
- GABRQ
Mechanisms of action (all sources)
- Benzodiazepine receptor agonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
- GABRG1 POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- CNR1
- OPRK1
- ACHE
- HTR6
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- KAT2B
- HTR3A
- MLNR
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- HCAR2
- GIPR
- GHSR
- MC5R
- MMP1
- FYN
- PTGS1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Anxiety Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- GABA Agents
- GABA Modulators
- Hypnotics and Sedatives
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
- Benzodiazepine
ATC classes
Cross-references
Synonyms
- Azor
- NIRAVAM
- XANAX
- XANAX XR
- xanax
- alprozolam
- alzolam
- NSC-760140
- U-31,889
- U-31889
- Niravam
- Xanax
- Xanax xr
- Alprazolam civ
- Alcelam
- Algad
- Alpaz
- Alplax
- Alpram
- Alprax
- Alprazolamum
- Alprazolan
- Alpronax
- Alprox
- Alviz
- Alzam
- Alzolam
- Alzon;Anpress
- ApoAlpraz
- Bestrol
- Cassadan
- Constan
- Esparon
- Frontal
- Helex
- Intensol
- Ksalol
Reported adverse events
- Constipation
- Depression
- Fatigue
- Incontinence
- Akathisia
- Dizziness
- Hypotension
- Rash
- Disinhibition
- Irritability
- Nausea
- Insomnia
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