← SynDRA
MIRTAZAPINE
SynDRA canonical compound SYN0001307 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR3A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR2C
- ADRA2B
- ADRA2C
- HTR2A
- ADRA2A
- HTR3A
- ADRA1A
- HRH1
- Slc6a2
- SLC6A2
- Htr2c
- Htr2a
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- Adrenergic receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- ADRA2A ANTAGONIST
- Adrenergic receptor alpha-2 antagonist
- ADRA2C ANTAGONIST
- ADRA2B ANTAGONIST
- TADA2A ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2B
- ADGRF1
- ADORA3
- KCNH2
- KDR
- MAOA
- MC3R
- MPG
- MUTYH
- NEIL1
- NEIL2
- NR1I2
- OGG1
- OPRD1
- PDE3A
- PDE4D
- PGR
- PTGS2
- S1PR1
- SAMHD1
- SLC6A3
- SLC6A4
- TARDBP
- TBXA2R
- TDG
- HTR1D
- HRH3
- HDAC6
- CYP2C9
- ADRB1
- ADRB2
- AGTR1
- APLNR
- ATAD5
- C5AR1
- CBX1
- CX3CR1
- CYP1A2
- CYP2C19
- CYP2D6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic Agents
- Adrenergic alpha-2 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Anti-Anxiety Agents
- Antidepressive Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
ATC classes
Cross-references
Synonyms
- Mirataz
- REMERON
- REMERON SOLTAB
- Remeron
- mepirzapin
- mepirzepine
- mirtabene
- mirtazepine
- mirtazipine
- Mirtazapina
- 6-azamianserin
- Avanza
- Mirtazapin
- Mirtazapine anhydrous
- Norset
- Promyrtil
- Rexer
- ORG-3770
- Remeron soltab
- Zispin
- Axit
- Azamianserin
- Mepirzapin
- Mepirzepine
- Mirtabene
- Mirtaz
- Mirtazapinum
- Mirtazepine
- Mirtazipine
- Mirtazon
- Remergil
- Remergon
- Celltech brand of mirtazapine
- Mundogen brand of mirtazapine
- Organon brand of mirtazapine
- Remeron SolTab
- ORG 3770
Reported adverse events
- Dizziness
- Myalgia
- Nausea
- Tremor
- Constipation
- Somnolence
- Weight
- Asthenia
- Stevens-Johnson syndrome
- Agranulocytosis
- Hypomania
- Mania
Look up MIRTAZAPINE in the interactive SynDRA portal →