← SynDRA
CHLORCYCLIZINE
SynDRA canonical compound SYN0001300 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | allergic rhinitis |
|---|
| Disease area | allergy |
|---|
All known targets
Mechanisms of action (all sources)
- Histamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- ADRA2A
- KCNH2
- CHRM1
- CHRM2
- SLC6A3
- DRD1
- DRD3
- ACHE
- PGR
- KDR
- MAOA
- OPRM1
- PDE3A
- PDE4A
- SAMHD1
- PTGS1
- IDH1
- SLC6A2
- SLC6A4
- TBXA2R
- TDP1
- KAT2A
- HRH3
- HTR2B
- HTR1A
- ADORA3
- HDAC6
- GMNN
- GLP1R
- F2
- ESR1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- AR
- ALOX15B
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- chlorcycline
- chlorocycline
- perazyl
- chlorcyclizine hydrochloride
- chlorcyclizine HCl
- Clorciclizina
- Alergicide
- Perazyl
- Trihistan
- COMPD 47-282
- NSC-25246
- 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine
- M26C4IP44P
- NSC 25246
- Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-
- Chlorcycline
- Chlorocycline
- Chlorocyclizine
- Di-paralen
- Histantine
- Histachlorazene
- Compound 47-282
- Piparalene
- Chlorcyclizinum
- 1-(4-Chlorobenzhydryl)-4-methylpiperazine
- N-Methyl-N'-(4-chlorobenzhydryl)piperazine
- 1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine
- 1-[(4-Chlorophenyl)phenylmethyl]-4-methylpiperazine
- 1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazine
- 1-((4-Chlorophenyl)phenylmethyl)-4-methylpiperazine
- Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-
- chlorocyclizin
- (+-)-Chlorcyclizine
- RefChem:54775
- DTXCID5027988
- Piperazine, 1-(((4-chlorophenyl)phenyl)methyl)-4-methyl-
- R06AE04
Look up CHLORCYCLIZINE in the interactive SynDRA portal →