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ACEBUTOLOL
SynDRA canonical compound SYN0001289 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRB1 |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | hypertension | ventricular arrhythmias |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRB1 ANTAGONIST
- Beta-1 adrenergic receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ABCB1
- MAPK14
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK1
- OPRK1
- MAOA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HRH2
- HRH1
- OPRD1
- OPRM1
- HDAC6
- PDE3A
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic beta-Antagonists
- beta-Adrenergic Blocker
- Adrenergic Agents
- Adrenergic Antagonists
- Adrenergic beta-1 Receptor Antagonists
- Anti-Arrhythmia Agents
- Antihypertensive Agents
- Cardiovascular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sympathomimetics
ATC classes
- C07A · BETA BLOCKING AGENTS
- BETA BLOCKING AGENTS AND THIAZIDES
Cross-references
Synonyms
- ACEBUTOLOL HYDROCHLORIDE
- SECTRAL
- IL-17803A
- acebutolol HCl
- acebutolol hydrochloride
- (RS)-Acebutolol
- (+/-)-Acebutolol
- dl-Acebutolol
- C07AB04
- Acebrutololum
- Acebutololo
- Acebutololum
- Acetobutolol
- Neptal
- Prent
- Sectral
- Acebutolol HCL
- RP 21823
- Acebrutololum [INN-Latin]
- Acebutololum [INN-Latin]
- Acetobutolol [INN-Spanish]
- Dl-Acebutolol
- M & B 17803A
- Prent (TN)
- Sectral (TN)
- Acebutolol (USAN/INN)
- Acebutolol [USAN:INN:BAN]
- M&B-17803 A
- N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide
- N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide
- N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
- N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide
- (+-)-3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide
- (+-)-Acebutolol
- 3'-(Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide
- 3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide
- 3'-Acetyl-4'-(2-hydroxy-3-isopropylaminopropoxy)butyranilid
- 5'-Butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone
Reported adverse events
- Agranulocytosis
- Depression
- Dizziness
- Erythema
- Fatigue
- Nausea
- Rash
- Abnormal dreams
- Arthralgia
- Constipation
- Cough
- Dyspepsia
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