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NAFTIFINE
SynDRA canonical compound SYN0001254 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | fungal squalene epoxidase inhibitor |
|---|
| Indication | tinea corporis | tinea cruris | tinea pedis |
|---|
| Disease area | infectious disease |
|---|
All known targets
- SQLE
- EBP
- ERG1
- ERG2
- SIGMAR1
- crtN
Mechanisms of action (all sources)
- fungal squalene epoxidase inhibitor
- SQLE INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD3
- HTR2A
- ADRA1A
- ADRA2C
- CNR1
- DRD2
- ADORA1
- NFE2L2
- MLNR
- MC4R
- MC3R
- NR1I2
- MAOA
- L3MBTL1
- IDH1
- HTR3A
- HTR2C
- NPY1R
- OPRD1
- NR3C1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2B
- HRH2
- HTR1A
- CBX1
- ADORA3
- ADRA2A
- ADRA2B
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- CP2CJ
- CP2D6
- GPR32
- JUN
- RXFP1
Drug classes
- Anti-Infective Agents
- Antifungal Agents
- Allylamine Antifungal
ATC classes
- D01A · ANTIFUNGALS FOR TOPICAL USE
Cross-references
Synonyms
- NAFTIFINE HYDROCHLORIDE
- NAFTIN
- Naftin
- naftifine hydrochloride
- naftifungin
- naftifine HCl
- naftifin
- Naftifina
- Naft-500
- AW 105-843
- Naftifin
- Naftifinum
- Naftifine HCl
- Naftifina [INN-Spanish]
- Naftifine (INN)
- Naftifine [INN:BAN]
- Naftifinum[INN-Latin]
- Naftin (TN)
- SN 105-843
- N-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride
- (E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine
- (E)-N-Cinnamyl-N-methyl-1-naphthalinmethylamin
- (E)-N-Cinnamyl-N-methyl-1-naphthylmethylamin
- CHEMBL626
- 4FB1TON47A
- CHEBI:7451
- NAFTIFINE [INN]
- AW-105-843
- Naftifinum [INN-Latin]
- UNII-4FB1TON47A
- NAFTIFINE [MI]
- Prestwick2_001063
- Prestwick3_001063
- NAFTIFINE [VANDF]
- NAFTIFINE [WHO-DD]
- SCHEMBL49141
- BSPBio_001046
- BPBio1_001152
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