← SynDRA

CINALUKAST

SynDRA canonical compound SYN0001244 — structure-anchored drug synonym record

All known targets

• CYSLTR1

Mechanisms of action (all sources)

• leukotriene receptor antagonist
• CYSLTR1 ANTAGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• NR1I2
• PPARG
• ACHE
• PDE3A
• HTR2B
• KCNH2
• KDM4E
• MAOA
• MAPT
• MC3R
• MLNR
• NPY1R
• NR3C1
• OPRM1
• PDE4A
• HSD17B10
• PGR
• PTGS1
• PTGS2
• SLC29A1
• SLC6A2
• SLC6A3
• SLC6A4
• SMN1
• TBXA2R
• TP53
• HTR1A
• HRH3
• ADORA1
• CCKAR
• ADORA2A
• ADORA3
• ADRA1A
• ADRA2A
• ADRB1
• AGTR1
• ALDH1A1
• AR
• AVPR1A
• AVPR2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• AHR
• CP1A2
• CP2C9
• CP3A4
• CP3A7
• ESR2
• NF2L2

Cross-references

• PubChem CID: 6436135
• ChEMBL: CHEMBL283754
• DrugBank: DB00587
• ChEBI: CHEBI:126598
• KEGG: D02846
• TTD: D06PEB

Synonyms

• Ro 24-5913
• RO-24-5913
• RO-245913
• Cinalukast [USAN:INN]
• Ro-24-5913
• Cinalukast (USAN/INN)
• (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
• 3'-((E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
• 4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
• 4-[3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]anilino]-2,2-diethyl-4-oxobutanoic acid
• 5E1O433QAI
• CHEMBL283754
• CHEBI:126598
• Ro-245913
• NCGC00092300-01
• 4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
• Butanoic acid, 4-((3-(2-(4-cyclobutyl-2-thiazolyl)ethenyl)phenyl)amino)-2,2-diethyl-4-oxo-, (E)-
• Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-
• CAS-128312-51-6
• UNII-5E1O433QAI
• CINALUKAST [INN]
• CINALUKAST [USAN]
• SCHEMBL37964
• SCHEMBL37965
• MLS003899216
• Cinalukast, ~98% (HPLC)
• DTXSID1045742
• CHEBI:93279
• HMS3413E03
• HMS3677E03
• ZINC3803377
• Tox21_111191
• BDBM50064086
• AKOS024456917
• Tox21_111191_1
• DB00587
• NCGC00092300-02
• SMR002543511