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PRANLUKAST
SynDRA canonical compound SYN0001236 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CYSLTR2 |
|---|
| Mechanism of action | Leukotriene receptor antagonist |
|---|
| Indication | asthma | bronchospasm |
|---|
| Disease area | pulmonary |
|---|
All known targets
- CYSLTR1
- CYSLTR2
- GPR17
- IL5
- MUC2
- NFKB1
- NR1H4
- RNASE3
- TNF
- rep
Mechanisms of action (all sources)
- Leukotriene receptor antagonist
- CYSLTR1 ANTAGONIST
- Cysteinyl leukotriene receptor 1 antagonist
- CYSLTR2 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- PGR
- DRD3
- DRD1
- HTR1A
- OPRM1
- PDE4A
- SLC6A2
- SLC6A3
- ABCC4
- SAMHD1
- S1PR1
- PTGS1
- SHMT2
- GLP1R
- PDE3A
- MAOA
- HTR2B
- SLC6A4
- HRH3
- HDAC6
- GPR35
- GPR119
- FPR2
- GALNS
- ABCC1
- ABCC3
- ACHE
- ADGRF1
- ADORA1
- ADRA1A
- ADRA2A
- ADRB2
- AGTR1
- APLNR
- AR
- C5AR1
- CHRM1
- CHRM2
- CX3CR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- CLTR2
- CP2C9
- CP2D6
- CP3A7
- GPR32
- NTM1A
- NTMT1
- PPM1D
Drug classes
- Anti-Asthmatic Agents
- Hormone Antagonists
- Leukotriene Antagonists
- Respiratory System Agents
ATC classes
- R03D · OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Cross-references
Synonyms
- ONO-1078
- onon
- azlaire
- pranlukast hydrate
- Azlaire
- CCN-00401
- RS-411
- SB-205312
- Onon
- Azlaire (TN)
- Pranlukast (INN)
- N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
- ONO 1078
- ONO RS-411
- TB8Z891092
- DTXCID1023782
- pranlukastum
- RefChem:175724
- R03DC02
- C27H23N5O4
- MFCD00864631
- NCGC00181765-01
- PRANLUKAST [INN]
- Pranlukast [INN:BAN]
- SR-05000001474
- UNII-TB8Z891092
- Pranlukast (Standard)
- PRANLUKAST [MI]
- PRANLUKAST [MART.]
- SCHEMBL3693
- PRANLUKAST [WHO-DD]
- MLS006010078
- GTPL3634
- orb1310378
- SCHEMBL18058592
- SCHEMBL29349894
- SCHEMBL31756724
- CHEBI:94810
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