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DIMETHINDENE
SynDRA canonical compound SYN0001235 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | cholinergic receptor antagonist | histamine receptor antagonist |
|---|
| Indication | allergic rhinitis |
|---|
| Disease area | allergy |
|---|
All known targets
- HRH1
- CHRM1
- CHRM2
- CHRM3
- CHRM4
- CHRM5
Mechanisms of action (all sources)
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- CHRM1 ANTAGONIST
- CHRM2 ANTAGONIST
- CHRM3 ANTAGONIST
- CHRM4 ANTAGONIST
- CHRM5 ANTAGONIST
- cholinergic receptor antagonist
- histamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ADRA1A
- OPRM1
- HTR1A
- DRD1
- DRD3
- PIN1
- PDE3A
- PDE4A
- PGR
- ACHE
- POLI
- MAOA
- SLC6A2
- SLC6A3
- SLC6A4
- PTGS1
- HTR2B
- KDR
- ADORA3
- HRH3
- HDAC6
- GNAS
- GLP1R
- F2
- ESR1
- ATXN2
- AR
- ADRA2A
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Allergic Agents
- Antipruritics
- Dermatologic Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
Cross-references
Synonyms
- dimetindene
- dimetindene maleate
- dimethindene maleate
- Dimetindene
- Dimetindeno
- Dimethpyrindene
- Feniallerg
- Forhistal
- Dimethylpyrindene
- Dimetindenum
- Fengel
- Fenistil
- Foristal
- Pecofenil
- Triten
- Z 2001
- Dimetindene (INN)
- Dimetindene [INN:BAN]
- Dimetindeno [INN-Spanish]
- Dimetindenum [INN-Latin]
- Fenistil (TN)
- Dimethyl{2-[3-(2-pyridylethyl)inden-2-yl]ethyl}amine
- N,N-Dimethyl-3-(1-(2-pyridyl)ethyl)inden-2-ethylamin
- N,N-Dimethyl-N-(3-(1-(2-pyridyl)ethyl)-2-indenylethyl)amin
- N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine
- 1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)-(9CI)
- 2-(1-(2-(2-Dimethylaminoethyl)inden-3-yl)ethyl)pyridine
- Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-
- 2-(1-(2-(2-(DIMETHYLAMINO)ETHYL)INDEN-3-YL)ETHYL)PYRIDINE
- N,N-DIMETHYL-3-(1-(2-PYRIDINYL)ETHYL)-1H-INDENE-2-ETHANAMINE
- (+-)-Dimethindene
- RefChem:390723
- DTXCID002942
- D04AA13
- R06AB03
- 1H-Indene-1,3(2h)-Dione, 5,6-Dimethyl-2-Nitro-, Ion(1-)
- (+/-)-Dimethindene
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