← SynDRA

MEROPENEM

SynDRA canonical compound SYN0001232 — structure-anchored drug synonym record

All known targets

• bla OXA-48
• blaNDM-1
• blaVIM-2
• dacA
• dacB
• dacC
• pbpA
• ponA
• ska

Mechanisms of action (all sources)

• bacterial cell wall synthesis inhibitor
• dacB INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• ERBB2
• MMP1
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LCK
• KCNH2
• HTR6
• HTR2C
• HTR2B
• HTR2A
• HRH2
• HRH1
• HMGCR
• HDAC6
• FYN
• FLT1
• ESR2
• MMP9
• NPY1R
• NPY2R
• PTPRC
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2
• SIGMAR1
• SAMHD1
• PTGS2
• NR1I2
• PTGS1
• PTAFR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP1A2
• CP2D6
• CP3A7

Drug classes

• Anti-Bacterial Agents
• Anti-Infective Agents

ATC classes

• J01D · OTHER BETA-LACTAM ANTIBACTERIALS

Cross-references

• PubChem CID: 441130
• ChEMBL: CHEMBL127
• DrugBank: DB00760
• ChEBI: CHEBI:43968
• KEGG: D02222
• RxNorm: 1546029
• PDB: MEM
• Wikipedia: Meropenem
• TTD: D0O5FY
• LINCS BRD: BRD-K01612348

Synonyms

• MEROPENEM AND SODIUM CHLORIDE IN DUPLEX CONTAINER
• MERREM IV
• VABOMERE
• Vabomere
• meropenem hydrate
• merrem
• meropenem trihydrate
• Meropenem hydrate
• Meropenem trihydrate
• Meronem
• Meropenem (as trihydrate)
• Meropenem anhydrous
• Meropenem, anhydrous
• Merrem i.v.
• ICI 194,660
• ICI-194660
• NSC-759621
• SM-7338
• Meropenem component of vabomere
• Merrem
• MEPM
• MERONEM
• Meropen
• Mepem (TN)
• Meronem (TN)
• Meropen (TN)
• Meropenem (INN)
• Merrem (TN)
• Neopenem (TN)
• Merrem I.V. (TN)
• meropenem trihydrate (ep monograph)
• Meropenem Trihydrate
• ICI 194660
• FV9J3JU8B1
• meropenem (usp-rs)
• meropenem (usp impurity)
• Meropenem Hydrate

Reported adverse events

• Nausea
• Phlebitis
• Hypersensitivity
• Pain
• Rash
• Seizure
• Thrombocytopenia
• Vomiting
• Glossitis
• Injection site reaction
• Stevens-Johnson syndrome
• Death