← SynDRA

LINEZOLID

SynDRA canonical compound SYN0001228 — structure-anchored drug synonym record

All known targets

• MAOA
• MAOB
• Maob
• SDHA

Mechanisms of action (all sources)

• Bacterial 50S ribosomal subunit inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PTGS1
• CALML3
• ADORA1
• NPY1R
• MLNR
• MC3R
• LMNA
• KCNH2
• HTR3A
• NR3C1
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• HRH2
• NR1I2
• OPRD1
• HDAC6
• OPRK1
• OPRM1
• PDE3A
• PDE4D
• PGR
• PTGS2
• SAMHD1
• SCN5A
• SLC29A1
• SLC6A3
• SLC6A4
• TBXA2R
• HRH1
• GHSR
• ADORA2A
• CCKBR
• ADORA3
• ADRA1A
• ADRA2A
• ADRA2B
• ADRA2C

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ESR1

Drug classes

• Oxazolidinone Antibacterial
• Anti-Bacterial Agents
• Anti-Infective Agents
• Enzyme Inhibitors
• Protein Synthesis Inhibitors

ATC classes

• J01X · OTHER ANTIBACTERIALS

Cross-references

• PubChem CID: 441401
• ChEMBL: CHEMBL126
• DrugBank: DB00601
• ChEBI: CHEBI:63607
• KEGG: D00947
• RxNorm: 190376
• PDB: ZLD
• Wikipedia: Linezolid
• TTD: D07UYO
• LINCS BRD: BRD-K66876909

Synonyms

• LINEZOLID IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
• ZYVOX
• Zyvox
• linospan
• linox
• zyvox
• zyvoxid
• linezolid sodium chloride
• linezolide
• U 100766
• Linezolide
• Pnu-100766
• U-100,766
• U-100766
• Linezlid
• ZLD
• Zyvoxa
• Zyvoxam
• Zyvoxid
• PNU-100766
• Linezolid & VRC3375
• Linezolid [USAN:INN]
• Zyvox (TN)
• Zyvoxam (TN)
• Zyvoxid (TN)
• NDA 21-130 Zyvox (linezolid tablets)
• NDA 21-131 Zyvox for injection (linezolid injection)
• NDA 21-132 Zyvox oral suspension (linzolid oral suspension)
• Linezolid (JAN/USAN/INN)
• PNU-100766, U-100766, Zyvoxid, Zyvoxam, Linezolid
• 111GE017
• ISQ9I6J12J
• PNU 100766
• linezolid (usp monograph)
• linezolid (usp-rs)
• LINEZOLIDE
• PNU100766

Reported adverse events

• Headache
• Pruritus
• Lactic acidosis
• Myelosuppression
• Serotonin syndrome
• Thrombocytopenia
• Dizziness
• Eosinophilia
• Nausea
• Rash
• Stevens-Johnson syndrome
• Vertigo