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ENPROFYLLINE
SynDRA canonical compound SYN0001226 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
| Primary target(s) | PDE4A |
| Mechanism of action | Phosphodiesterase inhibitor |
All known targets
- ADORA2B
- PDE4A
- ADORA1
- ADORA2A
- ADORA3
- PDE4B
- Adora1
- Adora2a
- Adora3
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- PDE4A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- PLK1
- KCNH2
- KDR
- MAOA
- OPRM1
- PDE3A
- PGR
- POLI
- ADRA1A
- PTGS1
- RGS4
- SLC6A2
- SLC6A3
- SLC6A4
- TARDBP
- HTR2B
- HTR1A
- HSD17B10
- HRH3
- HPGD
- HDAC6
- GMNN
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- BLM
- ARSA
- AR
- ADRA2A
- TBXA2R
Drug classes
- Adenosine A2 Receptor Antagonists
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Purinergic Antagonists
- Purinergic P1 Receptor Antagonists
- Respiratory System Agents
Cross-references
Synonyms
- 3-Propylxanthine
- Enprofilina
- D-4028
- Enprofyllinum
- Nilyph
- Oxeze
- P 5679
- Enprofilina [INN-Spanish]
- Enprofylline [USAN:INN]
- Enprofyllinum [INN-Latin]
- Enprofylline (USAN/INN)
- 3,7-Dihydro-3-propyl-1H-purine-2,6-dione
- 3-Propyl-3,7-dihydro-purine-2,6-dione
- 3-n-Propylxanthine
- 3-propyl-3,7-dihydro-1H-purine-2,6-dione
- 3-propyl-7H-purine-2,6-dione
- 1H-Purine-2,6-dione, 3,7-dihydro-3-propyl-
- D 4028
- DT7DT5E518
- 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
- DTXCID7025186
- CHEBI:126237
- RefChem:590853
- NCGC00015824-07
- EINECS 255-201-8
- UNII-DT7DT5E518
- Lopac-P-5679
- ENPROFYLLINE [INN]
- ENPROFYLLINE [USAN]
- A1BD3
- Lopac0_000910
- ENPROFYLLINE [MART.]
- MLS000069700
- ENPROFYLLINE [WHO-DD]
- SCHEMBL156402
- orb1306380
- 3-Propylxanthine (enprofylline)
- SCHEMBL18029491
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