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GW7647
SynDRA canonical compound SYN0001212 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARA AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- RXRA
- USP1
- NR1H4
- PPARD
- PPARG
- NR3C1
- PLK1
- PIN1
- NR5A1
- NR4A1
- ALDH1A1
- POLB
- NR2E1
- NR2C1
- NR1I2
- NPSR1
- NFKB1
- PMP22
- POLI
- POLH
- MPHOSPH8
- POLK
- RAPGEF4
- RECQL
- RGS4
- SIRT5
- TDP1
- THRB
- TP53
- USP2
- VDR
- NFE2L2
- MAPT
- ALOX15
- MAPK1
- ALOX15B
- ATAD5
- ATXN2
- BAZ2B
- BLM
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AICDA
- KSYK
- UBP1
- SYK
- RPGF4
- RPGF3
- RAPGEF3
- PNMT
- PE2R2
- NTMT1
- NTM1A
- NNMT
- HNMT
- COMT
- GPX4
- GNMT
- GEMI
- GCR
- GAMT
- FUMH
- FABP2
- EZH2
- CP3A4
- CP2C9
- WDR48
Cross-references
Synonyms
- CHEMBL21241
- GW-7647
- GW647
- GW 7647
- NTL2A9CAZ7
- GW-7647X
- RefChem:1086342
- MFCD06798379
- Tocris-1677
- SR-01000076211
- GW 7647; GW 7647; GW 7647X; GWalpha 7647;
- C29H46N2O3S
- PKNYXWMTHFMHKD-UHFFFAOYSA-N
- 2VN
- Spectrum5_001993
- UNII-NTL2A9CAZ7
- Lopac-G-6793
- Lopac0_000530
- MLS002172452
- SCHEMBL361372
- GTPL2674
- orb1308239
- CHEBI:70778
- cid_3392731
- EX-A132
- HMS2233O16
- HMS3261J21
- HMS3268M21
- HMS3372N10
- HMS3412B12
- HMS3650E20
- HMS3676B12
- HMS3749K21
- Tox21_500530
- BDBM50099491
- AKOS024456744
- CCG-204620
- CS-7924
- EBC-419043
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