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VANOXERINE
SynDRA canonical compound SYN0001195 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | SLC6A3 |
|---|
| Mechanism of action | Dopamine uptake inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Dopamine uptake inhibitor
- SLC6A3 INHIBITOR
- dopamine reuptake inhibitor
- SLC6A3 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- SLC6A4
- SLC6A2
- SIGMAR1
- OPRK1
- OPRM1
- ABL1
- POLK
- MPHOSPH8
- MTOR
- NFE2L2
- NFKB1
- NPC1
- NPSR1
- OPRD1
- PMP22
- RAB9A
- PTH1R
- MAPK1
- RGS4
- SAMHD1
- SMAD3
- SMN1
- TDP1
- THPO
- TP53
- TRIM24
- TSHR
- MAPT
- LMNA
- ALDH1A1
- KDM4A
- ALOX15B
- ARSA
- ATAD5
- ATXN2
- AURKA
- BLM
- BRD4
- BRPF1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ADRB2
- M4K2
- MDM2
- MDM4
- MDR1
- MLLT3
- NSD2
- PPARD
- RXFP1
- SC6A3
- STK33
- SYK
- TNNC1
- TNNI3
- TNNT2
- TPO
- LOX12
- KSYK
- GLI3
- CP1A2
- ALOX12
- ANDR
- APAF
- BARD1
- BRCA1
- CP19A
- CP2C9
- GEMI
- CP2CJ
- CP2D6
- CP3A7
- DRD2
- ESR1
- ESRRA
- UBE2N
Drug classes
- Dopamine Uptake Inhibitors
Cross-references
Synonyms
- Vanoxerina
- GBR-12909
- Vanoxerinum
- Vanoxerine [INN]
- D-052
- Vanoxerina [INN-Spanish]
- Vanoxerinum [INN-Latin]
- Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)-, dihydrochloride
- 1-(2 (Bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine di-hcl
- 1-(2-(Bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine
- 1-(2-bis-[4-FLUOROPHENYL]-METHOXYETHYL)-4-(3-PHENYL-2-PROPYL)PIPERAZINE
- 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
- GBR12909
- Vanoxeamine
- CHEMBL281594
- CHEBI:64089
- 90X28IKH43
- 67469-69-9 (free base)
- GBR 12909;I893
- 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine
- Piperazine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)-
- CAS-67469-78-7
- UNII-90X28IKH43
- Tocris-0421
- SpecPlus_000900
- Lopac-D-052
- Prestwick0_000386
- Prestwick1_000386
- Prestwick2_000386
- Prestwick3_000386
- Biomol-NT_000010
- Lopac0_000446
- BSPBio_000571
- DivK1c_006996
- SCHEMBL246574
- SPBio_002492
- BPBio1_000629
- BPBio1_001141
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