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TRIENTINE
SynDRA canonical compound SYN0001146 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CA14 |
|---|
| Mechanism of action | chelating agent |
|---|
| Indication | Wilson's disease |
|---|
| Disease area | metabolism |
|---|
All known targets
- CA14
- CA1
- CA12
- CA2
- CA3
- CA4
- CA5A
- CA5B
- CA6
- CA7
- CA9
- Ca13
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD3
- ADORA1
- NR1I2
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- KDM4E
- LMNA
- MAOA
- MC3R
- MLNR
- NPY1R
- NR3C1
- HRH2
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAT1
- SAT2
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HRH3
- HRH1
- ADORA2A
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Copper Chelating Activity
- Metal Chelating Activity
- Metal Chelator
- Chelating Agents
- Sequestering Agents
- Copper Chelator
- chelating agent
ATC classes
- A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Cross-references
Synonyms
- CLOVIQUE
- CUVRIOR
- Cuvrior
- SYPRINE
- Syprine
- TRIENTINE HYDROCHLORIDE
- triethylene tetramine
- triethylene tetramine dihydrochloride
- trien
- 1,8-Diamino-3,6-diazaoctane
- trientine hydrochloride
- triethylenetetramine
- trientine dihydrochloride
- trientine tetrahydrochloride
- trientine HCl
- Trientina
- Trethylenetetramine
- Triethylene tetraamine
- Triethylene tetramine
- NSC-443
- Trientine HCl
- triethylenetetramine HCl
- SMR000058543
- AC1NUQ0M
- MLS000069683
- SCHEMBL205201
- CHEMBL1200783
- CTK0I9735
- DTXSID80419994
- XPVOJYDIBHYVFL-UHFFFAOYSA-N
- Pharmakon1600-01505675
- NSC759164
- NSC158271
- AKOS027276425
- NSC-158271
- NSC-759164
- 1, N,N'-bis(2-aminoethyl)-, tetrahydrochloride
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